Sarcopenia and fragility fractures: molecular and clinical evidence of the bone-muscle interaction

The Journal of Bone and Joint Surgery. American Volume
Umberto TarantinoRoberto Bei

Abstract

➤ Bone and muscle tissues are in close relationship, and the aging process is a factor involved in the loss of the functionality of both bones and muscles.➤ Sarcopenia and osteoporosis are linked from a biological and functional perspective and are related to an increased fracture risk in the elderly.➤ The increased fracture risk in sarcopenic and osteoporotic subjects is due to the decline of muscle mass and strength, the decrease in bone mineral density, and limited mobility.

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Citations

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