Sarcopenia Definition: The Position Statements of the Sarcopenia Definition and Outcomes Consortium.

Journal of the American Geriatrics Society
Shalender BhasinPeggy M Cawthon

Abstract

To develop an evidence-based definition of sarcopenia that can facilitate identification of older adults at risk for clinically relevant outcomes (eg, self-reported mobility limitation, falls, fractures, and mortality), the Sarcopenia Definition and Outcomes Consortium (SDOC) crafted a set of position statements informed by a literature review and SDOC's analyses of eight epidemiologic studies, six randomized clinical trials, four cohort studies of special populations, and two nationally representative population-based studies. Thirteen position statements related to the putative components of a sarcopenia definition, informed by the SDOC analyses and literature synthesis, were reviewed by an independent international expert panel (panel) iteratively and voted on by the panel during the Sarcopenia Position Statement Conference. Four position statements related to grip strength, three to lean mass derived from dual-energy x-ray absorptiometry (DXA), and four to gait speed; two were summary statements. The SDOC analyses identified grip strength, either absolute or scaled to measures of body size, as an important discriminator of slowness. Both low grip strength and low usual gait speed independently predicted falls, self-reported...Continue Reading

References

Sep 1, 1979·American Journal of Epidemiology·W B KannelW P Castelli
Jan 17, 1977·JAMA : the Journal of the American Medical Association·W R Barclay
Feb 1, 1993·The Journal of Nutrition·W J Evans, W W Campbell
Apr 29, 1998·American Journal of Epidemiology·R N BaumgartnerR D Lindeman
Jun 16, 2000·Journal of the American Geriatrics Society·L J MeltonB L Riggs
Jun 24, 2000·Annals of the New York Academy of Sciences·R N Baumgartner
Mar 30, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·E M LauP Sambrook
Feb 18, 2003·Journal of the American Geriatrics Society·Anne B NewmanUNKNOWN Health Aging And Body Composition Research Group
May 16, 2003·JAMA : the Journal of the American Medical Association·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Dec 23, 2003·Journal of the American Geriatrics Society·Anne B NewmanUNKNOWN Health ABC Study Investigators
Apr 9, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Diana KuhUNKNOWN Musculoskeletal Study Team
Apr 20, 2005·Contemporary Clinical Trials·W Jack RejeskiMarco Pahor
May 5, 2005·JAMA : the Journal of the American Medical Association·Jane A CauleySteven R Cummings
Apr 7, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Dan MellströmClaes Ohlsson
May 4, 2006·JAMA : the Journal of the American Medical Association·Anne B NewmanTamara B Harris
May 16, 2008·International Journal of Epidemiology·Robert G CummingMelisa Litchfield
Apr 16, 2010·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN European Working Group on Sarcopenia in Older People
Jul 2, 2010·The New England Journal of Medicine·Shehzad BasariaShalender Bhasin
Jan 6, 2011·JAMA : the Journal of the American Medical Association·Stephanie StudenskiJack Guralnik
Jan 11, 2011·International Journal of Epidemiology·Martijn HuismanDorly J H Deeg
Jun 7, 2011·Journal of the American Medical Directors Association·John E MorleyUNKNOWN Society on Sarcopenia, Cachexia and Wasting Disorders Trialist Workshop
May 25, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·John A ShepherdMichael A Levine
May 15, 2013·Journal of the American Medical Directors Association·Wei-Ju LeeUNKNOWN ILAS Research Group
Apr 17, 2014·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Stephanie A StudenskiMaria T Vassileva
Aug 25, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Subashan PereraStephanie A Studenski
May 6, 2016·Journal of the American Geriatrics Society·Celestin MissikpodeRobert B Wallace
Jan 18, 2017·PloS One·Charlotte BeaudartOlivier Bruyère
Sep 11, 2018·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·Ingebjørg Lavrantsdatter KyrdalenHeidi Ormstad
Oct 13, 2018·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2
Jan 4, 2020·Aging Clinical and Experimental Research·Esra Ates BulutAhmet Turan Isik
Mar 25, 2020·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Conny Tm van OostromLeo Tm van der Ven
Apr 18, 2020·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kristine M ErlandsonTodd T Brown
Jun 9, 2020·Journal of Oral and Maxillofacial Pathology : JOMFP·P M Sunil
Jul 8, 2020·Journal of the American Geriatrics Society·Peggy M CawthonShalender Bhasin
Jul 8, 2020·Journal of the American Geriatrics Society·Sheena M PatelPeggy M Cawthon
Jul 8, 2020·Journal of the American Geriatrics Society·Todd M ManiniPeggy M Cawthon
Jul 8, 2020·Journal of the American Geriatrics Society·Gregory J GrosickiRoger A Fielding

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Citations

Jun 14, 2020·Journal of the American Geriatrics Society·Ayşe Merve AtaLevent Özçakar
Jun 14, 2020·Journal of the American Geriatrics Society·Shalender Bhasin, Peggy M Cawthon
Apr 18, 2020·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kristine M ErlandsonTodd T Brown
Jul 8, 2020·Journal of the American Geriatrics Society·Sheena M PatelPeggy M Cawthon
Jul 8, 2020·Journal of the American Geriatrics Society·Matteo Cesari, George A Kuchel
Sep 17, 2020·Journal of the American Geriatrics Society·Alexandra J MayhewParminder Raina
Jul 15, 2020·BMC Geriatrics·Steven PhuGustavo Duque
Aug 2, 2020·Aging Clinical and Experimental Research·Jean-Yves ReginsterRoger A Fielding
Sep 16, 2020·Aging Clinical and Experimental Research·Emanuele Rocco VillaniKatie Palmer
Sep 20, 2020·The Journal of Clinical Endocrinology and Metabolism·Cassandra SmithItamar Levinger
Nov 27, 2020·Journal of Cachexia, Sarcopenia and Muscle·Akihiko KitamuraShoji Shinkai
Jan 9, 2021·Seminars in Reproductive Medicine·Navira SamadFrances Milat
Oct 4, 2020·Current Opinion in Supportive and Palliative Care·Ana Paula Trussardi FayhMaria Cristina Gonzalez
Jan 16, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Nicholas C HarveyEugene McCloskey
Feb 7, 2021·Journal of the American Medical Directors Association·Lukus Klawitter, Ryan McGrath
Feb 18, 2021·Journal of the American Medical Directors Association·Ryan McGrath
Nov 25, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Vitor H F OliveiraRafael Deminice
Apr 4, 2021·International Journal of Environmental Research and Public Health·Anna K StuckReto W Kressig
Apr 9, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Nicholas C HarveyEugene McCloskey
Apr 11, 2021·Advances in Nutrition·Susan B RobertsSarah Booth
Apr 15, 2021·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Masashi YamashitaKagami Miyaji
May 7, 2021·Journal of the American Geriatrics Society·Michal S BeeriAron S Buchman
May 7, 2021·Climacteric : the Journal of the International Menopause Society·H H NguyenA J Vincent
Apr 8, 2021·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Brian C Clark, Richard G Carson
May 21, 2021·Calcified Tissue International·Monica C TemboJulie A Pasco
Jun 2, 2021·Journal of Cachexia, Sarcopenia and Muscle·Jonas JohanssonSameline Grimsgaard

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