Sarcopenia is associated to an impaired autonomic heart rate modulation in community-dwelling old adults

Archives of Gerontology and Geriatrics
Verônica Porto de FreitasRafael Pereira

Abstract

The aims of this study were to compare the autonomic heart control parameters from sarcopenic and non-sarcopenic community-dwelling elders. This is a cross-sectional study including 76 community-dwelling old adults, which was clinically stratified as sarcopenic or non-sarcopenic, according to the current recommendations. They were submitted to 5-min recordings of successive RR intervals. The analysis of the RR intervals variability was carried out in time (mean RR, RMSSD, pNN50, SDNN and triangular index) and frequency domains (LFnu, HFnu and LF/HF ratio), and with nonlinear methods (SD1, SD2, and D2). The parameters of autonomic heart rate modulation (AHRM) were adjusted for potential confounders: sex, diabetes, beta-blockers use, cardiovascular disease, body mass index and physical activity level, smoking habit. Normality of the data was tested by Kolmogorov-Smirnov test and, since most variables did not exhibit a normal distribution the Mann-Whitney test was used to compare the parameters of AHRM. The significance level was set as p ≤ 0.05 and all statistical procedures were performed with SPSS®. Adjusted parameters of AHRM obtained from time domain and nonlinear methods were significantly different between sarcopenic and no...Continue Reading

Citations

Jul 3, 2020·Age and Ageing·Pinar SoysalAhmet Turan Isik
Sep 17, 2019·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Galit WeinsteinDavid Tanne
Aug 11, 2020·Calcified Tissue International·Panagiotis AnagnostisDimitrios G Goulis

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