Sarcopenia Is Associated with High Pulse Pressure in Older Women

Journal of Aging Research
Hélio José Coelho JúniorRicardo Yukio Asano

Abstract

Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. Methods. One hundred and thirty community-dwelling Brazilian older women (65.4 ± 6.3 years) were recruited to participate in this study. Data on body composition (via bioelectrical impedance measurements), cardiovascular parameters (using an automatic and noninvasive monitor), and muscle function (using a 3-meter gait speed test) were measured. Results. Sarcopenic older women (n = 43) presented higher levels of pulse pressure (PP) (60.3 ± 2.6 mmHg) and lower muscle function (0.5 ± 0.0 m/s) compared with nonsarcopenic subjects (n = 87) (53.7 ± 1.5 mmHg; 0.9 ± 0.0 m/s) (P < 0.05). Linear regression analysis demonstrated a significantly negative association between skeletal muscle index (SMI) and PP levels (β = -226, P < 0.05). Furthermore, sarcopenic older women showed a 3.1-fold increased risk of having higher PP levels compared with nonsarcopenic women (IC = 1.323-7.506) (P < 0.05). Conclusion. Sarcopenic older women showed lower musc...Continue Reading

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Citations

Jan 23, 2016·Geriatrics & Gerontology International·Juliano Bergamaschine Mata DizVinicius Cunha Oliveira
Sep 21, 2016·Mediators of Inflammation·Hélio José Coelho JuniorBruno Rodrigues
Dec 29, 2016·Blood Pressure·Hélio José Coelho JuniorMarco Carlos Uchida
Jan 12, 2017·São Paulo Medical Journal = Revista Paulista De Medicina·Hélio José CoelhoMarco Carlos Uchida
Nov 20, 2018·Gerontology & Geriatric Medicine·Raphael Miranda RamosClaudio de Oliveira Assumpção
Oct 25, 2017·Journal of Aging Research·Thiago Matheus da Silva SousaBruno Bavaresco Gambassi
Jun 29, 2017·Clinical and Experimental Pharmacology & Physiology·Alexander J RodríguezDavid Scott
Jun 27, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Isabel N SchellingerUwe Raaz
Jul 3, 2019·Gerontology & Geriatric Medicine·Raphael Miranda RamosClaudio de Oliveira Assumpção
Apr 15, 2017·Journal of Aging Research·Hélio José Coelho JuniorMarco Carlos Uchida
Jul 31, 2018·Journal of Aging Research·Hélio José Coelho-JúniorBruno Rodrigues
Aug 25, 2021·Experimental Gerontology·Douglas G J McKechnieS Goya Wannamethee

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Statistical Package for the Social Sciences ( SPSS

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