SARS-CoV-2 Disease Adjuvant Therapies and Supplements Breakthrough for the Infection Prevention.

Alessio Danilo InchingoloGianna Dipalma


The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a high-risk viral agent involved in the recent pandemic stated worldwide by the World Health Organization. The infection is correlated to a severe systemic and respiratory disease in many cases, which is clinically treated with a multi-drug pharmacological approach. The purpose of this investigation was to evaluate through a literature overview the effect of adjuvant therapies and supplements for the SARS-CoV-2 infection. The research has analyzed the advantage of the EK1C4, by also assessing the studies on the resveratrol, vitamin D, and melatonin as adjuvant supplements for long hauler patients' prognosis. The evaluated substances reported important benefits for the improvement of the immune system and as a potential inhibitor molecules against SARS-CoV-2, highlighting the use of sartans as therapy. The adjuvant supplements seem to create an advantage for the healing of the long hauler patients affected by chronic symptoms of constant chest and heart pain, intestinal disorders, headache, difficulty concentrating, memory loss, and tachycardia.


Dec 1, 1995·American Journal of Respiratory and Critical Care Medicine·T L BonfieldM Berger
Nov 1, 1996·American Journal of Respiratory and Critical Care Medicine·P J Barnes
Nov 1, 1996·American Journal of Respiratory and Critical Care Medicine·I IwamotoA Nakao
May 8, 1999·Journal of Pineal Research·C Kaur, E A Ling
Jul 5, 2002·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·Eliaz Kaufman, Ira B Lamster
May 7, 2004·The Journal of the American Dental Association·Stephen K Harrel, John Molinari
Jul 9, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Ricardo López de CiccoAndrés J Klein-Szanto
Aug 24, 2005·Virology Journal·Martin J VincentStuart T Nichol
Aug 30, 2005·American Journal of Respiratory and Critical Care Medicine·Pamela B Davis
Apr 21, 2006·International Journal of Experimental Pathology·Sandra C MillerGeorges J M Maestroni
May 30, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Chandana Haldar Alipreeta
Jun 6, 2007·Journal of Agricultural and Food Chemistry·Maria DagliaGabriella Gazzani
Oct 14, 2008·Genes & Nutrition·Jin-Taek HwangMyung Sunny Kim
Mar 24, 2009·Journal of Dentistry·Stefano Petti, Crispian Scully
Oct 6, 2009·The Journal of Biological Chemistry·Ana Shulla, Tom Gallagher
Apr 8, 2010·Journal of Periodontology·David M Dohan EhrenfestJean-Baptiste Charrier
Sep 28, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·David M Dohan EhrenfestJean-Baptiste Charrier
Sep 28, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·David M Dohan EhrenfestJean-Baptiste Charrier
Dec 3, 2010·Oral Diseases·N Spielmann, D T Wong
Mar 21, 2012·Critical Reviews in Immunology·Shankar Subramanian Iyer, Gehong Cheng
Nov 17, 2012·International Journal of Medical Sciences·Marco TatulloFrancesco Inchingolo
May 30, 2013·Nature Genetics·UNKNOWN GTEx Consortium
Mar 4, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Veronique S ChachayIngrid J Hickman
May 21, 2014·International Journal of Medical Sciences·Stefania CantoreDanila De Vito
Dec 3, 2014·Virus Research·Jean Kaoru Millet, Gary R Whittaker
Oct 16, 2015·Cell Host & Microbe·Gary WongGeorge F Gao
Dec 23, 2015·Advances in Virology·Yusuf AbbaMohamed Mustapha Noordin
Aug 24, 2016·The Eurasian Journal of Medicine·Mucahit EmetAhmet Hacimuftuoglu
Sep 3, 2016·International Journal of Oral Science·Chen-Zi ZhangXue-Dong Zhou
Oct 30, 2016·Proceedings of the National Academy of Sciences of the United States of America·Jung-Eun ParkTom Gallagher
Feb 15, 2017·BMC Infectious Diseases·Shih-Chao LinChi-Chen Lin
May 4, 2017·Seminars in Immunopathology·Rudragouda Channappanavar, Stanley Perlman
Jul 12, 2017·Frontiers in Microbiology·Denise E MorrisStuart C Clarke
Oct 21, 2017·Respirology : Official Journal of the Asian Pacific Society of Respirology·Yudong Yin, Richard G Wunderink

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