SARS-CoV-2 seroprevalence in students and teachers: a longitudinal study from May to October 2020 in German secondary schools.

BMJ Open
C. KirstenJakob Peter Armann

Abstract

To quantify the number of SARS-CoV-2 infections in secondary schools after their reopening in May 2020. Repeated SARS-CoV-2 seroprevalence study after the reopening of schools and 4 months later. Secondary school in Dresden, Germany. 1538 students grades 8-12 and 507 teachers from 13 schools. Serial blood sampling and SARS-CoV-2 IgG antibody assessment. Seroprevalence of SARS-CoV-2 antibodies in study population. Number of undetected cases. 1538 students and 507 teachers were initially enrolled, and 1334 students and 445 teachers completed both study visits. The seroprevalence for SARS-CoV-2 antibodies was 0.6% in May/June and the same in September/October. Even in schools with reported COVID-19 cases before the lockdown of 13 March, no clusters could be identified. Of 12 persons with positive serology five had a known history of confirmed COVID-19; 23 out of 24 participants with a household history of COVID-91 were seronegative. Schools do not play a crucial role in driving the SARS-CoV-2 pandemic in a low-prevalence setting. Transmission in families occurs very infrequently, and the number of unreported cases is low in this age group. These observations do not support school closures as a strategy fighting the pandemic in a l...Continue Reading

References

Mar 20, 2004·Pediatric Pulmonology. Supplement·Gary W Wong, Tai F Fok
Nov 22, 2005·Risk Analysis : an Official Publication of the Society for Risk Analysis·Chung-Min LiaoHuang-Min Liang
Feb 6, 2018·Journal of Infection and Public Health·Sharafaldeen Bin NafisahNora A Brazanji
Jan 25, 2020·The New England Journal of Medicine·Na ZhuUNKNOWN China Novel Coronavirus Investigating and Research Team
Apr 10, 2020·MMWR. Morbidity and Mortality Weekly Report·UNKNOWN CDC COVID-19 Response Team
Apr 10, 2020·The Lancet Child & Adolescent Health·Russell M VinerRobert Booy
Apr 18, 2020·Communicable Diseases Intelligence·UNKNOWN COVID-19 National Incident Room Surveillance Team
May 1, 2020·Journal of Clinical Microbiology·Elitza S TheelKamran Kadkhoda
Jun 11, 2020·Deutsches Ärzteblatt International·Jakob Peter ArmannReinhard Berner
Aug 8, 2020·The Lancet Child & Adolescent Health·Kristine MacartneyUNKNOWN NSW COVID-19 Schools Study Team
Oct 13, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Chih-Cheng LaiPo-Ren Hsueh
Dec 15, 2020·JAMA Network Open·Zachary J MadewellNatalie E Dean
Jan 9, 2021·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Lin T BrandalBrita A Winje

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Citations

Nov 4, 2021·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Roma ThammHannelore Neuhauser

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