Sasanquol, a 3,4-seco-triterpene alcohol from sasanqua oil, and its anti-inflammatory effect

Phytochemistry
T AkihisaT Tamura

Abstract

A novel 3,4-seco-triterpene alcohol, named sasanquol, was isolated from the non-saponifiable lipid of sasanqua oil from the seeds of Camellia sasanqua. Its structure was established to be 3,4-seco-D:B-friedobacchara-4,21-dien-3-ol by spectroscopic methods. This is the first example of naturally occurring triterpene with a D:B-friedobaccharane skeleton. The 50% inhibitory dose of this compound against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear inflammation (1 microgram per ear) in mice was 0.4 mg per ear.

Citations

Jun 3, 2015·Pakistan Journal of Biological Sciences : PJBS·Agus Sukito, Sanro Tachibana
Mar 25, 2008·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Jia ShenLijun Du
Jan 21, 2006·Angewandte Chemie·Quanbo XiongSeiichi P T Matsuda
Apr 21, 2009·Natural Product Reports·Victoriano DomingoAlejandro F Barrero
May 19, 2021·Bioorganic Chemistry·Ke ZhaoWei Wang
Feb 1, 2007·Journal of the American Chemical Society·Masaaki ShibuyaYutaka Ebizuka
Aug 21, 2007·Journal of the American Chemical Society·Silvia LodeiroSeiichi P T Matsuda

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