Scaffolded amino acids as a close structural mimic of type-3 copper binding sites

Chemical Communications : Chem Comm
H Bauke AlbadaRob M J Liskamp

Abstract

We report the use of triazacyclophane (TAC)-scaffolded amino acids as a structural mimic for 3-histidine metal-binding sites in metalloproteins, especially for the mimicry of type-3 copper binding sites as are present in hemocyanin, tyrosinase and catechol oxidase.

References

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Citations

Jan 17, 2012·Journal of Medicinal Chemistry·Christopher J ArnuschYechiel Shai
Dec 15, 2015·Journal of the American Chemical Society·Eyal GolubItamar Willner
Oct 13, 2015·Bioconjugate Chemistry·Mohammad Aref KhalilyMustafa O Guler
Jun 19, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Enrico FaggiIgnacio Alfonso
Jan 19, 2010·Analytical and Bioanalytical Chemistry·Zita CsendesIstván Pálinkó

Related Concepts

Copper
Catechol Oxidase
Hemocyanin
Histidine
Indicators
Metalloproteins
Dioxygen
Infrared Spectrophotometry
Spectrophotometry, Ultraviolet
Raman Optical Activity Spectroscopy

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