Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics.

Angewandte Chemie
Samuel Suárez-PantigaAbraham Mendoza

Abstract

The development of more active C-H oxidation catalysts has inspired a rapid, scalable, and stereoselective assembly of multifunctional piperazines through a [3+3] coupling of azomethine ylides. A combination of visible-light irradiation and aluminum organometallics is essential to promote this transformation, which introduces visible-light photochemistry of main-group organometallics and sets the basis for new and promising catalysts.

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Citations

Aug 18, 2017·Angewandte Chemie·Jorge Otero-FragaAbraham Mendoza
Sep 11, 2018·Chemical Communications : Chem Comm·Moumita MajumdarVikas Kumar
Jun 25, 2016·Beilstein Journal of Organic Chemistry·Zhishi YeMingji Dai
Oct 21, 2017·Angewandte Chemie·Kilian ColasAbraham Mendoza
Jun 27, 2020·Organic Process Research & Development·Elisa Martínez-CastroAbraham Mendoza

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Methods Mentioned

BETA
NMR
X-ray

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