PMID: 19927770Nov 26, 2009Paper

Scalp metastasis from small cell carcinoma of the rectum: an unusual case

La Tunisie médicale
Lobna AyadiTahya Sellami-Boudawara

Abstract

Cutaneous metastasis of rectal carcinoma is a rare event. It occurs in 4% of all patients with rectal cancer. Skin metastasis of rectal cancer are usually detected near the initial tumor, especially in the periumbilical region; but they rarely occur in the scalp. To report a new case of scalp metastases from rectal tumor. Our patient was a 63-year old male with a history of small cell carcinoma of the rectum who subsequently developed a single nodule of the scalp of 4cm. Histopathological analysis revealed a small cell carcinoma infiltrating the dermis and subcutaneous tissue. The patient underwent palliative chemotherapy but his disease continued to progress. In contrast to the prior cases of scalp metastases reported in the literature, ours is the first documentation of such an occurrence from rectal small cell carcinoma. The early diagnosis of skin metastases in these patients is very important because it can alter treatment.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Australasian Journal of Dermatology
Aleksandar L KrunicKeith Lopatka
Journal of the American Academy of Dermatology
A M Kazakis, W R Parish
South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
P R Hull, I T Hay
© 2022 Meta ULC. All rights reserved