Scalp topographic mapping of middle-latency somatosensory evoked potentials in normal aging and dementia

Neurophysiologie clinique = Clinical neurophysiology
R FerriM C Stefanini

Abstract

Middle-latency somatosensory evoked potentials (MLSEPs) were recorded in four groups of subjects: 13 normal young controls (mean age, 17.9 years). 11 normal elderly (mean age, 66.9 years), 11 patients with dementia of Alzheimer's type (DAT: mean age, 70.5), and four with vascular dementia (mean age, 79.3). MLSEPs in normal elderly showed an increase in the latency of P22, N30, P45, N60, and P100, and in the amplitude of N60. DAT patients also presented such changes; however, the increase in the amplitude of N60 was much more evident than that found in normal aging and was accompanied by a significant increase in amplitude of P45. Patients with vascular dementia tended to show longer latencies and larger amplitudes than the other groups. The increase in amplitude of P45 and N60 in MLSEPs seems to be characteristically associated with normal aging and the development of dementia. It is suggested that the mechanism of such functional changes might be correlated with the structural and neurochemical changes accompanying neuronal loss in these conditions.

References

Sep 1, 1975·Archives of Neurology·V C HachinskiL Symon
Dec 1, 1975·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·E De Renzi, P Nichelli
Jun 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·R Nitsch, M Frotscher
Sep 1, 1991·Electroencephalography and Clinical Neurophysiology·R Kakigi, H Shibasaki
Jul 1, 1991·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·R Kakigi, H Shibasaki
Sep 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·G AbbruzzeseE Favale
May 1, 1984·Journal of Clinical Neuropsychology·A SunderlandJ Gleave
Sep 1, 1982·The American Journal of Psychiatry·B ReisbergT Crook
Nov 1, 1994·Neurophysiologie clinique = Clinical neurophysiology·R FerriP Bergonzi
May 24, 1994·Proceedings of the National Academy of Sciences of the United States of America·G TononiG M Edelman
Nov 1, 1995·Psychophysiology·L García-LarreaF Mauguière
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Mar 8, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Jyrki T Kuikka

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Citations

Feb 24, 2001·Neurophysiologie clinique = Clinical neurophysiology·S BostantjopoulouA Kazis
Apr 27, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Dominik Zumsteg, Heinz Gregor Wieser
Jan 28, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Davide V MorettiPaolo M Rossini
Aug 11, 2004·Behavioral Neuroscience·Claudio BabiloniPaolo Maria Rossini
Feb 19, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hans-Christian Hansen
Oct 23, 2008·Neurophysiologie clinique = Clinical neurophysiology·W J G van de WassenbergN M Maurits
Mar 11, 2008·Neurophysiologie clinique = Clinical neurophysiology·W van de WassenbergN Maurits
Sep 18, 2007·Progress in Neurobiology·Paolo M RossiniJohn Polich
May 7, 2004·The European Journal of Neuroscience·Claudio BabiloniPaolo M Rossini
Dec 27, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Claudio BabiloniPaolo M Rossini
May 3, 2005·Brain Research Bulletin·Claudio BabiloniPaolo Maria Rossini
Mar 23, 2006·Technology in Cancer Research & Treatment·Robert D PearlsteinPaul Haerich
May 13, 2008·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Wilma J G van de WassenbergNatasha M Maurits

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