Scandinavian Multicenter Acute Subdural Hematoma (SMASH) Study: Study Protocol for a Multinational Population-Based Consecutive Cohort

Neurosurgery
Jiri BartekAsgeir S Jakola

Abstract

Traumatic acute subdural hematomas (ASDHs) are associated with high rate of morbidity and mortality, especially in elderly individuals. However, recent reports indicate that the morbidity and mortality rates might have improved. To evaluate postoperative (30-d) mortality in younger vs elderly (≥70 yr) patients with ASDH. Comparing younger and elderly patients, the secondary objectives are morbidity patterns of care and 6 mo outcome according to Glasgow outcome scale (GOS). Finally, in patients with traumatic ASDH, we aim to provide prognostic variables. This is a large-scale population-based Scandinavian study including all neurosurgical departments in Denmark and Sweden. All adult (≥18 yr) patients surgically treated between 2010 and 2014 for a traumatic ASDH in Denmark and Sweden will be included. Identification at clinicaltrials.gov is NCT03284190. We expect to provide data on potential differences between younger vs elderly patients in terms of mortality and morbidity. We hypothesize that elderly patients selected for surgery have a similar pattern of care as compared with younger patients. We will provide functional outcome in terms of GOS at 6 mo in younger vs elderly patients undergoing ASDH evacuation. Finally, clinical...Continue Reading

Associated Clinical Trials

References

Jan 1, 1979·Acta neurochirurgica·J Hernesniemi
Jan 1, 1992·British Journal of Neurosurgery·B CagettiG Viale
Feb 11, 1991·Journal of Neurosurgery·J E WilbergerD L Diamond
Dec 1, 1989·Journal of Neurosurgery·M A HowardH R Winn
Jan 1, 1988·Acta neurochirurgica·K HaselsbergerL M Auer
Jan 1, 1993·Neurologia Medico-chirurgica·S HatashitaS Takagi
Apr 24, 1999·Acta neurochirurgica·G D MurrayA Unterberg
Jun 28, 2011·World Neurosurgery·Federico Alfonso Landriel IbañezAntonio Carrizo

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