Scanning electron-microscope studies of the endothelium of aortic allografts in the rabbit: effect of azathioprine, prednisolone and promethazine on early cellular invasion

The Journal of Pathology
M A Reidy, D E Bowyer


Aortic allografts in rabbits were observed by scanning electron microscopy 24 hr after transplantation. The extent of the leucocytic invasion could be precisely and reproducibly measured. Azathioprine and prednisolone, whether alone or in combination, given on three occasions--10 hr before, immediately after and again 10 hr after surgery, significantly inhibited the cellular invasion. Promethazine produced a slight, but not statistically significant, effect.


Nov 1, 1991·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·D PlissonnierJ B Michel
Nov 11, 2005·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Tomoyuki WadaTetsuo Hadama
Jan 1, 1997·Surgery Today·K SakataY Morishita

Related Concepts

Ascending Aorta Structure
Azathioprine Sulfate
Cell Density
Cell Motility
Electron Microscopy
Transplantation, Homologous

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.