Scanning laser Doppler flowmeter study of retinal and optic disk blood flow in glaucomatous patients

American Journal of Ophthalmology
M T NicolelaS M Drance

Abstract

To examine blood flow in the retina and optic nerve head of patients with primary open-angle glaucoma. Retinal and optic nerve head blood flow of glaucoma patients and control subjects of similar age and gender were measured in arbitrary units with the Heidelberg Retina Flowmeter, a scanning laser Doppler flowmeter (Heidelberg Engineering, Heidelberg, Germany). A total of 33 glaucoma patients and 29 control subjects were included in this study. Microvascular blood volume, flow, and velocity were analyzed in four areas of the retina approximately 100 microns from the edge of the optic disk (two temporal, one superior, and one inferior), in one area of the neuroretinal rim, and in the lamina cribrosa. The glaucoma patients had significantly decreased blood volume, flow, and velocity in one temporal retinal area (P < .006) and in blood volume in the inferior retinal area (P = .04). They also had significantly decreased blood volume, flow, and velocity in the lamina cribrosa (P < .0004), which also had more areas the investigators judged to be avascular compared to control subjects (P < .0001). No differences between glaucoma and control subjects in the blood flow measurements of the neuroretinal rim were found. These findings sugg...Continue Reading

References

Feb 1, 1977·The British Journal of Ophthalmology·R A Hitchings, G L Spaeth
Nov 1, 1977·Archives of Ophthalmology·B SchwartzS L Fishbein
Apr 1, 1975·The British Journal of Ophthalmology·R W Morgan, S M Drance
Sep 1, 1992·Experimental Eye Research·C E RivaR D Shonat
Jul 1, 1986·Archives of Ophthalmology·J E GrunwaldB L Petrig
Jan 15, 1988·American Journal of Ophthalmology·S M DranceR J Britton
Aug 1, 1995·American Journal of Ophthalmology·A HarrisB J Martin
Jan 1, 1993·The British Journal of Ophthalmology·P RojanapongpunB J Morrison
Apr 1, 1996·Journal of Glaucoma·G MichelsonM J Groh
Jun 15, 1981·Applied Optics·R Bonner, R Nossal

❮ Previous
Next ❯

Citations

Mar 2, 1999·Microvascular Research·S R ChamotC E Riva
May 13, 1999·Acta Ophthalmologica Scandinavica·M Iester
May 30, 2001·Survey of Ophthalmology·G A Cioffi
Jul 23, 1999·Survey of Ophthalmology·J R Piltz-Seymour
Dec 11, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Renuka Bathija
Nov 18, 2000·American Journal of Ophthalmology·O FindlL Schmetterer
Mar 3, 2001·American Journal of Ophthalmology·O GeyerD M Silver
Nov 30, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Enrique Adan SatoItaru Kimura
Dec 17, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Rita EhrlichAlon Harris
Nov 13, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Da-Wen LuYi-Hao Chen
Mar 10, 2001·Acta Ophthalmologica Scandinavica. Supplement·M CiancagliniL Mastropasqua
Oct 30, 2015·Current Eye Research·Zvia Burgansky-EliashDan Gaton
Feb 21, 2016·Acta Ophthalmologica·Luís Abegão PintoIngeborg Stalmans
Jan 6, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yoshimasa KurodaNagahisa Yoshimura
Feb 3, 2009·American Journal of Ophthalmology·Sunil DeokuleRobert N Weinreb
Nov 4, 2008·Acta Ophthalmologica·Alexandra LukschLeopold Schmetterer
Nov 26, 2010·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Vickie H Y WongAlgis J Vingrys
Jul 5, 2001·American Journal of Ophthalmology·J R Piltz-seymourJ Dupont
Jan 9, 2009·Clinical & Experimental Ophthalmology·Mika HarjuEija Vesti
Nov 20, 1998·American Journal of Ophthalmology·C P AvilaW R Freeman
Nov 30, 1999·American Journal of Ophthalmology·W B Wilson
Oct 22, 2008·Progress in Brain Research·Charles E Riva, Benedetto Falsini
Nov 12, 2015·BioMed Research International·B QuillC J O'Brien
Jun 24, 2008·Current Eye Research·Andreas J KreisTien Y Wong
Apr 5, 2005·Current Eye Research·Andrew LamJuan Grunwald
Jan 25, 2007·Acta Ophthalmologica Scandinavica·Gunilla BjärnhallAlbert Alm
Jun 5, 2003·Journal of Glaucoma·Adael S SoaresBalwantray C Chauhan
Nov 10, 2010·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Jiann-Shyan HerYung-Hsiang Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.