Scanning laser polarimetry with variable corneal compensation in primary angle-closure glaucoma

Ophthalmology
Catherine Jui-Ling LiuWen-Ming Hsu

Abstract

To evaluate the diagnostic sensitivity of scanning laser polarimetry in primary angle-closure glaucoma (PACG) as compared with that in primary open-angle glaucoma (POAG) and to compare the retinal nerve fiber layer (RNFL) distribution between PACG and POAG. Prospective, comparative, observational cases series. One eye each of 58 PACG patients and 51 POAG patients. Scanning laser polarimetry with variable corneal compensation (GDx VCC). GDx VCC temporal-superior-nasal-inferior-temporal (TSNIT) parameters, including TSNIT average, TSNIT standard deviation, superior average, and inferior average, as well as the nerve fiber indicator (NFI). By using a logistic marginal regression model that defined an abnormal test as P<5% for each of the TSNIT parameters or NFI > or = 31, we found that diagnostic sensitivities of the GDx VCC parameters were similar (all Ps>0.05) in PACG and POAG despite the differences in refraction error (P = 0.017), axial length (P<0.001), and disc diameters (vertical, P = 0.031; horizontal, P = 0.002) between these 2 forms of glaucoma. The between-group similarity in the diagnostic sensitivity remained true either when all eyes were considered together or in each severity group, based on the visual field scorin...Continue Reading

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Citations

Jun 19, 2009·Current Opinion in Ophthalmology

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