PMID: 20120516Feb 3, 2010Paper

Scars in depression: is a conceptual shift necessary to solve the puzzle?

Psychological Medicine
Marieke WichersF Peeters

Abstract

Although clinical findings suggest that in the aftermath of depression a process of 'scarring' may ensue, research examining the issue of 'scars' (including biological, psychological and cognitive changes) has remained largely inconclusive. This paper proposes a new approach to the concept of 'scars' that is (i) based on a dimensional view of depression, (ii) uses methods that take into account the dynamic interplay between the person and his context, (iii) differentiates between scars following depression and scars following the factor that actually caused the depression such as stress and (iv) introduces a dynamic view of the concept of 'scars' in that it hypothesizes that scars can wax and wane. This approach may stimulate the discovery of new entries in the puzzle underlying the ontogenesis of vulnerability and resilience. Furthermore, it may provide insights that help to develop new therapies for depression.

References

Nov 1, 1991·Journal of Abnormal Psychology·C Hammen
Nov 1, 1991·Psychological Medicine·C F DugganR M Murray
Jan 1, 1988·Behaviour Research and Therapy·A M Zeiss, P M Lewinsohn
Sep 1, 1987·The Journal of Nervous and Mental Disease·M Csikszentmihalyi, R Larson
May 17, 1995·Journal of Affective Disorders·D Q Barge-SchaapveldM W De Vries
Jul 1, 1994·Psychological Bulletin·J C Coyne
Nov 1, 1996·The American Journal of Psychiatry·M T SheaM B Keller
May 1, 1997·Psychological Bulletin·G L FlettL Krames
Dec 5, 2002·The Psychiatric Clinics of North America·Lewis L JuddHagop S Akiskal
Jun 6, 2003·Journal of Abnormal Psychology·Steven R H Beach, Nader Amir
Mar 3, 2004·Journal of Abnormal Psychology·Leyland C Sheppard, John D Teasdale
Oct 7, 2004·Archives of General Psychiatry·Johan OrmelWilma Vollebergh
Apr 6, 2006·Psychological Assessment·Filip De FruytFrédéric Rouillon
May 17, 2006·Psychological Medicine·Ari SolomonPeter M Lewinsohn
Jul 5, 2006·Archives of General Psychiatry·Zindel V SegalTom Buis
Dec 22, 2006·Psychiatry Research·Udo DannlowskiThomas Suslow
Apr 24, 2007·Clinical Psychology Review·Stephanie L Burcusa, William G Iacono
May 15, 2007·The Journal of Emergency Medicine·Abu N G A KhanSteven Davidson
Sep 4, 2007·The British Journal of Psychiatry : the Journal of Mental Science·Marieke WichersJim Van Os
Nov 8, 2007·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Robert A PhilibertAnup Madan
Dec 19, 2007·Journal of Consulting and Clinical Psychology·Christopher G BeeversSusan Nolen-Hoeksema
Feb 13, 2008·Journal of Abnormal Psychology·Catherine B StroudAnne Moyer
Jun 10, 2008·Epigenetics : Official Journal of the DNA Methylation Society·Tim F OberlanderAngela M Devlin
Jul 17, 2008·The American Journal of Psychiatry·Aaron T Beck

❮ Previous
Next ❯

Citations

Nov 26, 2014·Development and Psychopathology·Sylia WilsonWilliam G Iacono
Mar 1, 2012·The Psychiatric Clinics of North America·Andrew G Ryder, Yulia E Chentsova-Dutton
Oct 15, 2013·Psychophysiology·Uma VaidyanathanWilliam G Iacono
May 28, 2015·Depression and Anxiety·Christian HakulinenMarkus Jokela
Mar 11, 2015·European Psychiatry : the Journal of the Association of European Psychiatrists·R ZahnJ Moll
Apr 22, 2015·European Psychiatry : the Journal of the Association of European Psychiatrists·M van WinkelF Peeters
Nov 15, 2011·Neuroendocrinology·A T Spijker, E F C van Rossum
Jan 28, 2017·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Denny Borsboom
Nov 28, 2017·Psychological Medicine·Hanna M van LooKenneth S Kendler
Apr 6, 2019·Journal of Youth and Adolescence·Joseph R CohenNeus Barrantes-Vidal
Oct 8, 2018·Brain and Neuroscience Advances·Alexander Kaltenboeck, Catherine Harmer
Mar 25, 2021·Current Directions in Psychological Science·Janice K Kiecolt-GlaserAnnelise A Madison
Apr 6, 2021·Alzheimer's & Dementia : Translational Research & Clinical Interventions·Breno S DinizUNKNOWN on behalf of the PACt‐MD Study Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.