Scattering phase function spectrum makes reflectance spectrum measured from Intralipid phantoms and tissue sensitive to the device detection geometry.

Biomedical Optics Express
Stephen C KanickBrian W Pogue

Abstract

Reflectance spectra measured in Intralipid (IL) close to the source are sensitive to wavelength-dependent changes in reduced scattering coefficient ([Formula: see text]) and scattering phase function (PF). Experiments and simulations were performed using device designs with either single or separate optical fibers for delivery and collection of light in varying concentrations of IL. Spectral reflectance is not consistently linear with varying IL concentration, with PF-dependent effects observed for single fiber devices with diameters smaller than ten transport lengths and for separate source-detector devices that collected light at less than half of a transport length from the source. Similar effects are thought to be seen in tissue, limiting the ability to quantitatively compare spectra from different devices without compensation.

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Citations

Nov 2, 2014·Biomedical Optics Express·Stephen Chad KanickBrian W Pogue
Jul 27, 2015·Journal of Dairy Science·B AernoutsW Saeys
Jan 16, 2015·Physics in Medicine and Biology·Nico BodenschatzAlwin Kienle

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