Schistosoma haematobium infection and CD4+ T-cell levels: a cross-sectional study of young South African women

PloS One
Elisabeth KleppaEyrun Floerecke Kjetland

Abstract

Schistosoma (S.) haematobium causes urogenital schistosomiasis and has been hypothesized to adversely impact HIV transmission and progression. On the other hand it has been hypothesized that HIV could influence the manifestations of schistosomiasis. In this cross-sectional study, we explored the association between urogenital S. haematobium infection and CD4 cell counts in 792 female high-school students from randomly selected schools in rural KwaZulu-Natal, South Africa. We also investigated the association between low CD4 cell counts in HIV positive women and the number of excreted schistosome eggs in urine. Sixteen percent were HIV positive and 31% had signs of urogenital schistosomiasis (as determined by genital sandy patches and / or abnormal blood vessels on ectocervix / vagina by colposcopy or presence of eggs in urine). After stratifying for HIV status, participants with and without urogenital schistosomiasis had similar CD4 cell counts. Furthermore, there was no significant difference in prevalence of urogenital schistosomiasis in HIV positive women with low and high CD4 cell counts. There was no significant difference in the number of eggs excreted in urine when comparing HIV positive and HIV negative women. Our findi...Continue Reading

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References

Dec 9, 1998·Clinical and Experimental Immunology·A KalinkovichZ Bentwich
Sep 22, 2000·Clinical Immunology : the Official Journal of the Clinical Immunology Society·F X Lü
Sep 28, 2002·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Dawit WoldayZvi Bentwich
Sep 2, 2003·Nature Reviews. Immunology·Rick M Maizels, Maria Yazdanbakhsh
Oct 23, 2004·The Journal of Infectious Diseases·Michael BrownAlison M Elliott
Mar 19, 2005·The Journal of Infectious Diseases·Per KallestrupHenrik Ullum
Feb 14, 2006·AIDS·Eyrun F KjetlandSvein Gunnar Gundersen
May 18, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Per KallestrupHenrik Ullum
Sep 1, 2007·Current Opinion in Infectious Diseases·W Evan Secor, J Bruce Sundstrom
Sep 22, 2009·BMC Infectious Diseases·Shimelis AssefaTechalew Shimelis
Nov 26, 2009·International Journal of STD & AIDS·A C WeintrobB K Agan
Dec 10, 2009·The American Journal of Tropical Medicine and Hygiene·Eyrun Floerecke KjetlandLisette Van Lieshout
Mar 3, 2011·The American Journal of Tropical Medicine and Hygiene·Jennifer A DownsDaniel W Fitzgerald
Jun 7, 2011·The Open AIDS Journal·Jeanne Françoise KayibandaJean Philippe Gatarayiha
Dec 7, 2011·The American Journal of Tropical Medicine and Hygiene·Peter Mark JourdanEyrun Floerecke Kjetland
Jan 17, 2012·Trends in Parasitology·Eyrun F KjetlandPatricia D Ndhlovu
Feb 14, 2012·Current Opinion in HIV and AIDS·W Evan Secor
Apr 5, 2013·PLoS Neglected Tropical Diseases·Ingrid Elise Amlie HegertunEyrun Floerecke Kjetland
Aug 21, 2013·Tropical Medicine & International Health : TM & IH·Martial L Ndeffo MbahAlison P Galvani
Apr 5, 2014·Lancet·Daniel G ColleyCharles H King

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Citations

Apr 12, 2016·International Journal for Parasitology·Vanessa ChristinetJutta Reinhard-Rupp
Feb 7, 2018·The American Journal of Tropical Medicine and Hygiene·Soledad ColombeJennifer A Downs
Jul 3, 2018·PLoS Neglected Tropical Diseases·Soledad ColombeJennifer A Downs
Feb 8, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Daniel P OʼBrienVanessa Christinet
Nov 22, 2018·Frontiers in Immunology·Christian Schwartz, Padraic G Fallon
Dec 5, 2019·Tropical Diseases, Travel Medicine and Vaccines·Sergey YegorovRupert Kaul
Nov 7, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Pragna PatelW Evan Secor
Dec 15, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Solrun SøftelandEyrun Floerecke Kjetland

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