PMID: 6129940Jan 1, 1982Paper

Schistosoma mansoni: incorporation and metabolism of protein amino acids in vitro

Comparative Biochemistry and Physiology. B, Comparative Biochemistry
L H Chappell, E Walker


1. The amino acid composition of total proteins in six stages of the life cycle of Schistosoma mansoni was determined by routine autoanalysis of acid hydrolysates. Aspartate, glutamate and glycine were consistently the most abundant protein amino acids in all stages. 2. Incorporation of each of the protein amino acids into adult and egg proteins was determined using 72 hr cultures in complex media. Incorporation rates varied widely and there was no correlation between abundance in protein and the rate of incorporation. 3. Only five amino acids were interconverted to other amino acids which were themselves incorporated into worm and egg proteins (ala, arg, asp, gly, ser); of these only two (glu from ala and pro from arg) appeared to be of quantitative significance. Exogenous glucose yielded only three protein amino acids (ala, asp, glu). 4. The data are considered in the light of differences in egg and adult protein synthesis and with particular regard to potential chemotherapy at this level.


Jan 1, 1977·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·Y NagaiJ Pellegrino
Aug 15, 1975·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·C C De OliveiraJ Pellegrino
Aug 1, 1975·Experimental Parasitology·H L Asch, C P Read
Jan 1, 1976·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·H IsseroffM G Levy
Aug 1, 1974·International Journal for Parasitology·L H Chappell
Jan 1, 1972·Transactions of the Royal Society of Tropical Medicine and Hygiene·K S Warren
Nov 1, 1972·International Journal for Parasitology·J I BruceJ K Werner
Apr 1, 1970·Experimental Parasitology·E Toro-Goyco, M R Del Valle
Jan 1, 1980·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·E Walker, L H Chappell
Apr 7, 1980·Journal of Theoretical Biology·D N Wheatley, M S Inglis
Jan 1, 1982·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·E Walker, L H Chappell
Sep 11, 1981·Science·E M Conford, M E Huot
Dec 1, 1957·Archives of Biochemistry and Biophysics·D H HUG, C H WERKMAN

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.