PMID: 9184930Apr 1, 1997Paper

Schistosoma mansoni oviposition in vitro reflects worm fecundity in vivo: individual-, parasite age- and host-dependent variations

International Journal for Parasitology
R el RidiH Kamiya

Abstract

In an attempt to determine whether in vitro oviposition of adult S. mansoni reflects the fecundity status of worms in vivo, Mongolian gerbils and ICR, BALB/c and SCID mice were infected with about 100 cercariae and examined on an individual basis, 5-12 weeks later, for worm burden, counts of eggs in liver and small intestine, and for the rate of egg deposition of ex-vivo female worms cultured in vitro, singly or in pairs, over a 3-5 day incubation period. The percentage of egg-laying female worms and the number of eggs laid/female after 3 days in culture showed, like worm fecundity in vivo, wide inter-worm variability, especially in 5-, 6- and 12-week-old worms; varied significantly with the age of the parasite with a maximum level attained by worms of approximately 8 weeks of age; and differed in worms recovered from different host species and strains. The data taken together indicate that measuring the egg-producing ability of S. mansoni in vitro reflects the fecundity status of worms in vivo and additionally provides likely explanations for hitherto poorly understood findings on schistosome fecundity.

References

Nov 1, 1989·International Journal for Parasitology·J T JonesJ R Kusel
Feb 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·J K ActorJ A Berzofsky

❮ Previous
Next ❯

Citations

Sep 3, 2010·Experimental Parasitology·M C HoltfreterE C Reisinger
Jun 25, 2015·Revista Da Sociedade Brasileira De Medicina Tropical·Kedma de Magalhães LimaCélia Maria Machado Barbosa de Castro
Dec 10, 2002·Memórias do Instituto Oswaldo Cruz·Allen W CheeverZilton A Andrade
Oct 25, 2003·Revista Da Sociedade Brasileira De Medicina Tropical·Elaine Machado MartinezLuís Rey

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.