PMID: 43083Sep 1, 1979

Schistosomiasis--cancer: etiological considerations. A review

Acta Tropica
K G Brand

Abstract

Evidence for a causal connection between Schistosoma haematobium-infection and carcinoma of the urinary bladder is discussed. A group relationship of schistosomiasis cancer to cancers as+sociated with asbestosis, foreign body implants, and cicatrization is suggested on the basis of several criteria. Results of experimental foreign body tmuorigenesis in mice are presented and elaborated in relationship to schistosomiasis cancer. Carcinogenic development at the cellular level is discussed with emphasis on the essential role of tissue-environmental conditions, especially fibrotic changes and macrophage quiescence.

Related Concepts

Schistosoma Hematobium Infection
Urinary Bladder Diseases
Neoplasms
Schistosomiasis
Foreign-Body Reaction
Katayama Fever
Asbestosis
Squamous Cell Carcinoma
Macrophage
Schistosoma haematobium antigen

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