School-Based versus Community-Based Sampling for Trachoma Surveillance

The American Journal of Tropical Medicine and Hygiene
Joseph P SheehanJeremy D Keenan

Abstract

Trachoma surveillance is typically performed via random sampling of endemic districts. This strategy minimizes bias and allows examination of preschool children, but is also expensive. Surveillance for some other neglected tropical diseases is carried out in schools, which is logistically easier. In the present study, the prevalence of trachomatous inflammation-follicular (TF) from a population-based sample of children from each of 70 communities in Ethiopia was compared with the corresponding school-based estimate, which was calculated for each community by performing examinations in all primary schools in the district. The overall prevalence of TF was 39.1% (95% confidence interval [CI]: 35.0-43.1%) among children aged 1-9 years in the community-based sample and 18.8% (95% CI: 15.9-21.7%) among children in grades 1-3 of the school-based sample. School-based estimates of TF explained 35% of the variation in the community-based prevalences (P < 0.001). When TF prevalence was used as a diagnostic test for detecting a community with > 5% prevalence of ocular chlamydia, the area under the receiver operating characteristic curve was 0.73 (95% CI: 0.60-0.85) for the school-based sample and 0.71 (0.58-0.83) for the community-based sa...Continue Reading

References

Jul 30, 2003·Lancet·Anthony W SolomonDavid C W Mabey
Dec 30, 2004·Investigative Ophthalmology & Visual Science·Emily S WestSheila K West
Jan 18, 2006·American Journal of Epidemiology·Neil J Perkins, Enrique F Schisterman
Mar 11, 2009·Bulletin of the World Health Organization·Jeremiah NgondiPaul Emerson
Dec 23, 2009·PLoS Neglected Tropical Diseases·Emma M Harding-EschRobin L Bailey

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Citations

Aug 24, 2021·Survey of Ophthalmology·Fahd NaufalChristopher J Brady

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