Sci-Thur PM: YIS - 10: A new optically encoded single-fiber plastic scintillation detector for multi-point radiation dosimetry

Medical Physics
François Therriault-ProulxL Beaulieu

Abstract

To develop a new multi-point plastic scintillation detector (mPSD) that allows for simultaneous dose measurements at multiple points and uses a single optical guide. Two different prototypes were built. A two-point mPSD was built and light discrimination was based on the use of multiple color filters at the outputs of a network of optical fiber splitters. Light intensity was measured by an EMCCD camera. For the three-point mPSD, the light discrimination setup was replaced by a low-noise spectrometer. Depth-dose and profiles measurements were obtained on a 6 MV photon beam with the mPSDs inside a water phantom. An ion chamber was also used for comparison purpose. Finally, the three-point mPSD was tested under an Ir-192 high-dose-rate (HDR) brachytherapy dose delivery and compared to the treatment planning system. A good agreement was found between the measured and expected dose for both mPSDs. The average relative differences to the ion chamber measurement for the two-point mPSD were of (2.4 ± 1.6)% and (1.3 ± 0.8)%. For the three-point mPSD, these differences were of (2.3±1.1)%, (1.6±0.4)% and (0.32±0.19)%. The latter mPSD was shown very versatile, being able to measure dose from HDR brachytherapy with an average accuracy of (2...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.