PMID: 3764411Sep 1, 1986Paper

Science and trans-science in radiation risk assessment: child cancer around the nuclear fuel reprocessing plant at Sellafield, U.K

The Science of the Total Environment
D Crouch

Abstract

The assessment of health risks to the population from radionuclides in the environment is a complex and as yet incomplete science: biogeochemical mechanisms of environmental transfer and concentration are poorly understood; models of radionuclide metabolism rely largely on inconclusive and contradictory experiments with animals, and the principles by which results may be extrapolated to humans are unknown; uncertainties in the dosimetry of alpha-emitters in children and the foetus are acute; and chronic doubt persists over the magnitude of low-level dose-response for radiation carcinogenesis. To deny uncertainties of this nature is to court public distrust of scientific risk assessment; public confidence in nuclear power technologies might be strengthened through a more open discussion of the technical difficulties involved. These problems are described with reference to the assessment of cancer risks at a large nuclear facility in the north of England. The extent of uncertainties in a recent radiological risk assessment are found to be such that, should scientific concern persist over the exceptional incidence of child cancer in the locality, greater consideration should be given to a reappraisal of the risk calculation.

References

Mar 22, 1975·Lancet·F W Spiers
Mar 1, 1978·Health Physics·V E Archer
Jun 1, 1978·Health Physics·D RamsdenD C Fraser
Jan 1, 1977·Community Health·H J Dunster
Jan 19, 1985·Lancet·J Urquhart, J A Cutler
Jan 28, 1984·Lancet·J UrquhartJ Cutler
Aug 25, 1984·Lancet
Sep 15, 1984·Lancet·R H Clarke
Oct 13, 1984·Lancet·H J Dunster
May 1, 1984·The Science of the Total Environment·J R Cooper, J D Harrison
Jan 1, 1984·Leukemia Research·B I Lord, E G Wright
Mar 1, 1983·Health Physics·R J HickeyR C Clelland
Jan 1, 1983·Health Physics·R P LarsenR D Oldham
Jan 1, 1982·The Annals of Occupational Hygiene·M R BaileyA C James
Nov 1, 1981·Physics in Medicine and Biology·N Adams
Feb 1, 1980·Journal of Medical Genetics·P Oftedal, A G Searle
Jul 21, 1972·Science·A M Weinberg
May 22, 1981·Science·E Marshall

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Citations

Oct 24, 1987·British Medical Journal·D Crouch
Mar 24, 2010·Radiation and Environmental Biophysics·Richard WakefordMichael F G Murphy
Nov 19, 2010·Expert Review of Hematology·Richard WakefordGerald M Kendall
Oct 24, 1987·British Medical Journal·A M Lichtarowicz, J F Mayberry
Oct 24, 1987·British Medical Journal·K Dickersin
Oct 7, 1998·Perceptual and Motor Skills·J M Donovan

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