Scientific Presentation Award: The combination of axillary ultrasound and ultrasound-guided biopsy is an accurate predictor of axillary stage in clinically node-negative breast cancer patients.

American Journal of Surgery
Dana M HolwittJulie A Margenthaler

Abstract

The study aim was to determine the accuracy of axillary ultrasound (AUS) and fine-needle aspiration biopsy (FNAB)/needle core biopsy in axillary breast cancer staging. We reviewed 256 patients with clinically node-negative breast cancer who underwent AUS +/- FNAB/needle core biopsy. AUS-guided FNAB/needle core biopsy was compared with histopathology to determine sensitivity, specificity, negative predictive value, and positive predictive value. AUS-guided FNAB/needle core biopsy and final pathology were positive in 72 of 256 patients (28%). In 125 of 256 cases (49%), the AUS and final pathology were negative. Two of 110 patients had a false-positive FNAB (1.8%); both received neoadjuvant chemotherapy. Nine patients (8%) had a false-negative FNAB/needle core biopsy; the median size of lymph node metastasis was 3 mm. The sensitivity and specificity of AUS-guided FNAB/needle core biopsy was 71% and 99%, respectively, with a negative predictive value of 84% and a positive predictive value of 97%. AUS-guided FNAB/needle core biopsy is accurate in predicting the status of the axilla in 70% of clinically node-negative breast cancer patients. This technique is minimally invasive with a low complication rate and can obviate the need for...Continue Reading

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Citations

Aug 11, 2010·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Ichiro OginoTakashi Ishikawa
Sep 1, 2012·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Alberto TestoriSergio Orefice
Dec 17, 2009·World Journal of Surgery·Fatema Al MushawahJulie A Margenthaler
May 15, 2013·The Journal of Surgical Research·Leisha C ElmoreJulie A Margenthaler
Jul 24, 2012·Current Problems in Diagnostic Radiology·Habib RahbarConstance D Lehman
Jun 22, 2012·The Breast : Official Journal of the European Society of Mastology·M W H LeendersW H Schreurs
Jun 23, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S K SomasundaramM R S Keshtgar
Jul 9, 2013·European Journal of Radiology·Eun Young YooEun Sook Ko
Dec 11, 2014·The Breast : Official Journal of the European Society of Mastology·Jacqueline Ting Y LMichael Sugrue
Oct 6, 2018·Indian Journal of Surgical Oncology·Naresh Kumar SaidhaArijit Sen

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