PMID: 9169570Jun 1, 1997Paper

Scintigraphic evaluation of hepatic blood flow after intrahepatic portosystemic shunt (TIPS)

European Journal of Nuclear Medicine
J MenzelW Domschke

Abstract

In patients with liver cirrhosis a transjugularly placed intrahepatic portocaval shunt (TIPS) is a non-surgical portosystemic device which aims to reduce portal venous pressure. In comparison with Doppler sonography, we evaluated in 28 patients the diagnostic impact of liver perfusion scintigraphy (with technetium-99m diethylene triamine penta-acetic acid) in the assessment of changes in the hepatic blood flow after TIPS shunting. The arterial and portal contributions to hepatic flow were calculated from the areas under the biphasic time-activity curve. In the course of TIPS shunting, patency is threatened by reocclusion. Angiography is the gold standard for TIPS shunt reassessment. However, there is a need for a less invasive diagnostic procedure, such as scintigraphy or Doppler sonography, for the early detection of shunt insufficiency. Scintigraphy demonstrated that prior to TIPS shunting the portal venous contribution to hepatic perfusion was reduced to 29.2%, this reduction being due to portal hypertension. After TIPS placement a significant increase in portal venous perfusion was observed (38.2%; P<0.02). TIPS shunt occlusion was identified in patients by a significant reduction in the scintigraphically measured portal ve...Continue Reading

References

Jan 1, 1977·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·H J BiersackC Winkler
Jun 1, 1992·Baillière's Clinical Gastroenterology·G M RichterJ C Palmaz
Jul 1, 1992·Gut·M NavasaJ Rodés
Nov 1, 1991·Journal of Hepatology·L BolondiL Barbara
Jan 1, 1991·Digestive Diseases·D J van Leeuwen
Jul 15, 1989·Lancet·M RössleW Gerok
Mar 1, 1987·Gastroenterology·P BurnsA T Blei
May 1, 1995·AJR. American Journal of Roentgenology·G D DoddL A Santaguida
Jan 1, 1995·Gut·P A McCormickA K Burroughs
Mar 1, 1994·Journal of Gastroenterology and Hepatology·H C MengS S Wang
Aug 1, 1994·Gastroenterology·J G Sweeting
Feb 1, 1994·Journal of Clinical Ultrasound : JCU·A TalaveraL García
Jan 20, 1994·The New England Journal of Medicine·M RössleK Hauenstein
Sep 1, 1993·Cardiovascular and Interventional Radiology·H FerralJ G Letourneau
Sep 1, 1993·The Medical Clinics of North America·T G Brewer

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Citations

Jan 27, 2005·AJR. American Journal of Roentgenology·Claudia WeidekammTill R Bader
Jun 17, 1998·Cardiovascular and Interventional Radiology·R JalanD N Redhead
Apr 30, 1999·Gastroenterology·J Menzel

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