Scintigraphic Findings Beyond Ejection Fraction on Hepatobiliary Scintigraphy: Are They Correlated With Chronic Gallbladder Disease?

Clinical Nuclear Medicine
Chad T ChristensenKevin P Banks

Abstract

To determine if classically reported findings associated with chronic cholecystitis on hepatobiliary scintigraphy (HBS), such as delayed small bowel (SB) transit, slow gallbladder (GB) filling, and reversal of the normal GB and SB transit, are associated with a depressed GB ejection fraction (GBEF). The secondary objectives were to determine whether GBEF is correlated with the time of GB filling, time of SB transit, or reversal of normal GB/SB filling sequence. We hypothesize that an association between a depressed GBEF and these classical HBS findings could validate them as surrogate markers for chronic GB disease. We reviewed all HBS exams over a retrospective 16-month period. Data from 221 patients (mean age, 45.3 ± 15.2 years; 152 female and 69 male subjects) who underwent HBS with GBEF determination for evaluation of chronic symptoms concerning for biliary etiology met inclusion criteria. Classically reported findings for cholecystitis were recorded for each patient. Comparisons were made using t test and Fisher test analysis. Comparing exams with normal and abnormal GBEF values, there were no significant differences based on age, sex, GB fill time, normal versus delayed SB transit, and reversal of normal GB/SB filling seq...Continue Reading

References

Feb 1, 1983·AJR. American Journal of Roentgenology·W Al-SheikhA N Serafini
Mar 23, 2010·Clinical Nuclear Medicine·Murthy Chamarthy, Leonard M Freeman
Nov 17, 2010·Journal of Nuclear Medicine Technology·Mark TulchinskyUNKNOWN Society of Nuclear Medicine
Feb 22, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·John K DiBaiseMark Tulchinsky

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Citations

Mar 10, 2020·Clinical Nuclear Medicine·Lin ZhangHongming Zhuang
Nov 13, 2020·Clinical Nuclear Medicine·Kyu Yeoun Won, Chanwoo Kim

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