Scintimammography in the diagnosis of breast cancer

American Journal of Surgery
E J Clifford, C Lugo-Zamudio

Abstract

Mammography has a positive predictive value in the detection of breast cancer of 15% to 25%. Ten percent of patients with breast cancer present with normal mammograms; however, the false negative rate is increased in younger patients. The purpose of this study was to evaluate the effectiveness of Tc-99m Sestamibi imaging in the diagnosis of breast disease. Images were collected on 147 women. Patients were evaluated with a combination of physical examination, sonography, and mammography. Each patient received 20 millicuries of Tc-99m Sestamibi intravenously. Anterior and lateral images were obtained, the latter with the patient prone and the breast in the dependent position. One hundred seven patients showed no enhancement (negative scan). Seven of these patients were found at biopsy to have carcinoma. Five had ductal carcinoma in-situ (DCIS) with no associated mass, 1 had an incidental 3 mm focus of invasive ductal carcinoma (IDC), and 1 had a 5-cm cystic lesion with IDC. Forty-one patients showed focal enhancement on their scans (positive scan). Thirty-six were found to have either invasive or in-situ cancer. Four of the 5 patients with benign findings had sclerosing adenosis. The positive and negative predictive values for sc...Continue Reading

References

May 20, 1992·Journal of the National Cancer Institute·L MaN F Boyd
Jun 1, 1986·Cancer·H Høst, E Lund
Mar 1, 1993·Clinical Nuclear Medicine·M T KitapçiC Bekdik
Jun 2, 1993·Journal of the National Cancer Institute·E J FeuerT Tong

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Citations

Oct 2, 2001·Journal of Surgical Oncology·W Lawrence
Jun 28, 2005·Breast Cancer Research and Treatment·Feng WuHai-Bing Su
Apr 25, 2006·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Antonio PiñeroPascual Parrilla
Aug 1, 2000·Clinical Privilege White Paper
Aug 2, 2003·Breast Cancer Research and Treatment·Moishe LibermanJohn S Sampalis
Jun 13, 1998·Journal of the National Cancer Institute·J TolmosI Khalkhali
Jun 11, 1999·Clinical Nuclear Medicine·S BeaulieuA Rioux
Oct 3, 1999·Journal of the American Academy of Nurse Practitioners·A Stowe
Dec 20, 2002·AJR. American Journal of Roentgenology·Y R PariskyK Callahan
Mar 15, 2005·Seminars in Nuclear Medicine·Raymond Taillefer
Aug 16, 2000·Radiologic Clinics of North America·E D Pisano, C A Parham
Dec 31, 1998·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M DouekI Taylor
Jul 5, 2002·Clinical Radiology·D GopalanP J Ell
Feb 18, 2004·The Breast : Official Journal of the European Society of Mastology·P BerghammerH Sinzinger
Nov 23, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S MirzaeiH Kohn
Mar 9, 2002·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M H K LeideniusK A J von Smitten
Sep 2, 1998·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·I C SmithO Eremin

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