Scleral Thickness in Chinese Eyes

Investigative Ophthalmology & Visual Science
Ling ShenJost B Jonas

Abstract

We measured scleral thickness in eyes of Chinese, and assessed interregional differences and associations with age and axial length. Using light microscopy, we histomorphometrically measured scleral thickness at various locations in eyeballs from Chinese patients that had been enucleated due to retinoblastoma, uveal melanoma, or absolute painful glaucoma. The study included 281 globes from patients with a mean age of 24.8 ± 23.1 years (range, 1-83 years) and mean axial length of 24.3 ± 3.9 mm (range, 17.0-35.7 mm). In multivariate analysis in children aged ≤2 years, thicker posterior scleral thickness was marginally significantly associated with older age (P = 0.07; standardized correlation coefficient β, 0.21; correlation coefficient B, 62.2; 95% confidence interval [CI], -4.3,128.8) after adjusting for shorter axial length (P = 0.01). In participants aged ≥5 years, larger posterior scleral thickness was significantly associated only with shorter axial length (P < 0.001; β, -0.49; B, -24.1; 95% CI, -30.6,-17.6), but not with age (P = 0.93). The ratio of posterior scleral thickness to scleral thickness in the pars plana region decreased significantly with increasing axial length. The correlation coefficients were higher for the...Continue Reading

Citations

Dec 24, 2015·Acta Ophthalmologica·Jost B JonasSonghomitra Panda-Jonas
Aug 23, 2016·Acta Ophthalmologica·Jost B JonasSonghomitra Panda-Jonas
Jan 14, 2017·Retina·Jost B JonasSonghomitra Panda-Jonas
Mar 13, 2019·Acta Ophthalmologica·Li DongJost B Jonas
Aug 20, 2019·Acta Ophthalmologica·Rahul A Jonas, Leonard Holbach
Sep 10, 2020·Eye and Vision·Jost B JonasSonghomitra Panda-Jonas
Feb 24, 2019·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Jost B Jonas, Songhomitra Panda-Jonas
Oct 27, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jiamin XieXun Xu
Aug 15, 2019·Progress in Retinal and Eye Research·Craig BooteMichael J A Girard
Nov 16, 2016·Journal of Glaucoma·Jost B JonasSonghomitra Panda-Jonas
Jan 26, 2021·Asia-Pacific Journal of Ophthalmology·Fengju Zhang, Lingbo Lai

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