Scleroderma in Children and Adolescents: Localized Scleroderma and Systemic Sclerosis

Pediatric Clinics of North America
Suzanne C Li

Abstract

Scleroderma is a rare disease that has two main forms: localized scleroderma (LS) and systemic sclerosis (SSc). Both are chronic diseases, can present in different patterns (subtypes), and are associated with extracutaneous involvement in pediatric patients. Morbidity and mortality is much worse for juvenile SSc with patients at risk for life-threatening lung, heart, and other visceral organ fibrosis and vasculopathy. Mortality is extremely rare in juvenile LS, but morbidity is common, with patients at risk for severe disfigurement and functional impairment. Scleroderma treatment is directed towards controlling inflammation and managing specific problems. Early diagnosis can greatly improve outcome.

References

Nov 1, 1995·Mayo Clinic Proceedings·L S PetersonW P Su
Nov 1, 1996·Rheumatic Diseases Clinics of North America·F M Wigley, N A Flavahan
Jul 3, 1998·The American Journal of Dermatopathology·J E Torres, J L Sánchez
Apr 12, 2005·Pediatric Clinics of North America·Francesco Zulian
Sep 6, 2005·Arthritis and Rheumatism·Francesco ZulianUNKNOWN Juvenile Scleroderma Working Group of the Pediatric Rheumatology European Society (PRES)
Dec 22, 2005·Rheumatology·F ZulianUNKNOWN Juvenile Scleroderma Working Group of the Pediatric Rheumatology European Society (PRES)
Aug 5, 2006·The Journal of Pediatrics·Francesco ZulianLawrence F Eichenfield
Oct 21, 2006·Current Opinion in Rheumatology·Ronald M Laxer, Francesco Zulian
Nov 30, 2006·Arthritis and Rheumatism·Giorgia MartiniUNKNOWN Juvenile Scleroderma Working Group of the Pediatric Rheumatology European Society
Dec 7, 2006·Journal of the American Academy of Dermatology·Megha M Tollefson, Patricia M Witman
Dec 21, 2006·Clinical Rheumatology·Ramnath MisraAmita Aggarwal
Nov 3, 2007·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Mario Fabri, Nicolas Hunzelmann
Dec 1, 2007·The International Journal of Lower Extremity Wounds·Uwe WollinaKyrill Pramatarov
May 28, 2008·The British Journal of Dermatology·L Weibel, J I Harper
Jun 24, 2008·Journal of the American Academy of Dermatology·Stéphanie Christen-ZaechAmy S Paller
Jul 24, 2008·PloS One·Ausra MilanoMichael L Whitfield
Oct 16, 2008·Rheumatology·G MartiniUNKNOWN Juvenile Scleroderma Working Group of Paediatric Rheumatology European Society (PRES)
May 20, 2009·Archives of Dermatology·Justin J LeitenbergerHeidi T Jacobe
Mar 2, 2010·Arthritis Care & Research·Ariane L HerrickEileen M Baildam
May 29, 2010·Experimental Dermatology·Nicolas Hunzelmann, Thomas Krieg
Sep 17, 2010·The Journal of Rheumatology·Ivan FoeldvariChristopher P Denton
Sep 22, 2010·Archives of Dermatology·Stephanie Saxton-Daniels, Heidi T Jacobe
May 4, 2011·Cytokine·Katherine Kurzinski, Kathryn S Torok
May 10, 2011·Journal of the American Academy of Dermatology·Ximena WortsmanLaura Carreño
Jun 23, 2011·Radiology·Stefan SchanzMarius Horger
Sep 8, 2011·The British Journal of Dermatology·L WeibelJ I Harper
Oct 13, 2011·Nature Reviews. Rheumatology·C Egla Rabinovich
Dec 2, 2011·Current Rheumatology Reports·Jennifer Nashel, Virginia Steen
May 9, 2012·Pediatric Clinics of North America·Kathryn S Torok
Jun 5, 2012·Journal of the American Academy of Dermatology·Francesco ZulianGiorgia Martini
Apr 9, 2013·Journal of the American Academy of Dermatology·Christina E Kelsey, Kathryn S Torok
Apr 18, 2013·Arthritis Care & Research·Francesca Ingegnoli, Ariane L Herrick
Sep 17, 2013·The British Journal of Dermatology·M PiramJ Powell
Dec 18, 2013·The British Journal of Dermatology·M S PequetY E Chiu
Mar 17, 2015·Current Opinion in Rheumatology·Amber Young, Dinesh Khanna

❮ Previous
Next ❯

Citations

Jan 15, 2019·Journal of Paediatrics and Child Health·Fábio BarrosoManuela Selores
Jul 30, 2019·Frontiers in Immunology·Sangita KhatriKira Astakhova
Dec 2, 2019·World Journal of Pediatrics : WJP·Suzanne C Li, Rong-Jun Zheng
Jul 12, 2019·Frontiers in Immunology·Anne M StevensFrancesco Zulian
Nov 30, 2019·ACR Open Rheumatology·Eveline Y WuUNKNOWN Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry Investigators
May 23, 2019·Frontiers in Immunology·Kathryn S TorokTheresa T Lu
Sep 26, 2019·Frontiers in Pediatrics·David Avelar RodriguezEamonn Martin Quigley
Oct 28, 2020·Rheumatology International·Amra AdrovicOzgur Kasapcopur
Sep 22, 2020·Ultrasound in Medicine & Biology·Manuela PérezAndrea S Doria
Nov 25, 2020·Pediatric Clinics of North America·Mary M Buckley, C Egla Rabinovich
Sep 27, 2020·Rheumatology·Giorgia MartiniFrancesco Zulian
Mar 13, 2021·Rheumatology·Suzanne C LiUNKNOWN Childhood Arthritis and Rheumatology Research Alliance Localized Scleroderma Clinical and Ultrasound Study group
May 17, 2021·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Patrick CoitAmr H Sawalha
Jul 18, 2021·Pediatric Dermatology·Jacquelyn R Sink, Yvonne E Chiu
Aug 5, 2021·International Journal of Dermatology·Elena S Snarskaya, Kseniia D Vasileva
Jun 2, 2020·Indian Dermatology Online Journal·Renu GeorgeT Sathish Kumar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Basal Ganglia Cerebrovascular Disease

Basal ganglia cerebrovascular disease is a condition where the blood vessels in the basal ganglia are damaged or malfunction. Discover the latest research on basal ganglia cerebrovascular disease here.

Related Papers

Acta reumatológica portuguesa
Patrícia Andrade de MâcedoCláudia Goldenstein-Schainberg
The New England Journal of Medicine
Roger Kapoor, John R Kapoor
The Medical Clinics of North America
R C Siegel
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine
S Arimori
© 2022 Meta ULC. All rights reserved