Scleroderma in children

Best Practice & Research. Clinical Rheumatology
Francesco Zulian

Abstract

Juvenile scleroderma with its two varieties, juvenile localized scleroderma and systemic sclerosis (SSc), represents the third most frequent rheumatic disease in childhood. In juvenile SSc, new developments have been recently reported in the fields of classification and monitoring. The introduction of new classification criteria for adult SSc has stimulated new ideas on how to improve the performance of the provisional 2007 PRES/ACR/EULAR pediatric criteria. The introduction of a multidimensional severity score, named "J4S," which includes parameters on growth, skin, and internal organ involvement, has improved the approach to the patients in the daily practice to guide decision-making. In localized scleroderma, the wider application of clinical and instrumental scoring systems has greatly improved both assessment and monitoring. Finally, a multicenter consensus statement and long-term follow-up studies have confirmed the important role of methotrexate for the treatment.

Citations

Jun 4, 2019·Current Opinion in Pediatrics·Adriana G Peña-Romero, Maria T García-Romero
Mar 4, 2019·Annals of the Rheumatic Diseases·Francesco ZulianIvan Foeldvari
Jun 28, 2020·Current Rheumatology Reports·Francesco Zulian, Francesca Tirelli
Mar 8, 2020·European Radiology·Silvia Karem Janet Flores QuispeChiara Giraudo
May 16, 2019·Zeitschrift für Rheumatologie·M O BeckerB Maurer
Aug 7, 2019·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M O BeckerB Maurer
Oct 28, 2020·Rheumatology International·Amra AdrovicOzgur Kasapcopur
Sep 22, 2020·Ultrasound in Medicine & Biology·Manuela PérezAndrea S Doria
Mar 23, 2021·Clinical and Experimental Dermatology·L Weibel
Apr 27, 2021·Best Practice & Research. Clinical Rheumatology·Ivan Foeldvari, Kathryn S Torok
May 11, 2021·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Yo Han Oh, Soo Hyang Lee
Oct 27, 2021·Annals of Plastic Surgery·Maria YanSteven L Moran

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