Sclerotherapy of bleeding esophageal varices in schistosomiasis. Comparative study in patients with and without previous surgery for portal hypertension

Endoscopy
P SakaiH W Pinotti

Abstract

Ninety-seven patients with bleeding esophageal varices due to mansonic schistosomiasis were treated with endoscopic sclerotherapy. Seventy-five patients (Group I) had previously undergone surgery for portal hypertension and presented with bleeding recurrence. Twenty-two patients (Group II) had not undergone surgical treatment. The sclerotherapy technique employed was intravascular (IV) injections of ethanolamine in 40 patients and paravascular (PV) in 57 patients. Of a total of 38 (39%) patients who had bleeding recurrence, 27 (36%) were from Group I and 11 (50%) from Group II (p less than 0.005). Over a follow-up period of 48 to 132 months, 367 sessions of sclerotherapy were carried out in the 72 remaining patients from Group I (4.93 +/- 2.05). The remaining 16 patients from Group II needed 121 (7.56 +/- 2.70) sessions of sclerotherapy (p less than 0.001). Thus, sclerotherapy was effective in the control of rebleeding in 73 (97.3%) patients from Group I and 16 (72.7%) from Group II (p less than 0.05). We conclude that previous surgical treatment for portal hypertension in patients with mansonic schistosomiasis, greatly benefits treatment of rebleeding esophageal varices by endoscopic sclerotherapy. This is probably due to the ...Continue Reading

Citations

Sep 1, 2005·Surgical Infections·Alvaro Antônio Bandeira FerrazEdmundo Machado Ferraz
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Sep 1, 1996·Gastroenterology Clinics of North America·D E Elliott
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Sep 24, 2016·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Renata P ColaneriPaulo Herman
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Feb 5, 2021·Transactions of the Royal Society of Tropical Medicine and Hygiene·Guilherme G L CançadoLuciana C Faria
Mar 26, 2021·PLoS Neglected Tropical Diseases·Francesca TamarozziFederico G Gobbi

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