Sclerotic osseous metastases from renal cell carcinoma.

Skeletal Radiology
Darryl B SneagNikhil Ramaiya

Abstract

This case series describes and illustrates three cases of sclerotic osseous metastases from untreated renal cell carcinoma (RCC). RCC is commonly metastatic to the skeleton but almost always produces lytic metastases, with only three prior reports of sclerotic metastases identified in the literature. Sclerotic metastasis causing low back pain was the initial disease presentation in two of the three patients in this case series and the first manifestation of metastatic disease in one. The most common metastatic sites of RCC, i.e., retroperitoneal lymph nodes, lung, and liver, were not identified in any of the cases, and skeletal involvement with epidural extension was the only site of metastasis in two. Pathologic specimens from all three cases revealed RCC of high nuclear grade.

References

Jul 1, 1977·AJR. American Journal of Roentgenology·G S ForbesR R Hattery
Mar 1, 1975·The British Journal of Radiology·J F Reidy
Jan 1, 1992·Scandinavian Journal of Urology and Nephrology·C HenrikssonS Pettersson
Nov 1, 1981·The British Journal of Radiology·A I NeugutJ Smith
Nov 7, 1999·Skeletal Radiology·P T LiuM R Callstrom
Feb 23, 2002·The American Journal of Surgical Pathology·Mahul B AminMani Menon
Jan 28, 2003·Cancer·Theresa A GuiseKhalid S Mohammad
Feb 6, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·A Hari ReddiSuresh Mohla
Nov 25, 2003·The Journal of Urology·Igor FrankHorst Zincke
Apr 16, 2004·The New England Journal of Medicine·G David Roodman
Feb 3, 2005·Cell Research·Juan Juan YinKathleen Kelly
Sep 8, 2007·BJU International·Pierre I KarakiewiczJean-Jacques Patard
Dec 14, 2007·The Journal of Urology·Nathan E HoffmannMichael L Blute
Mar 13, 2010·Urology·Paul L CrispenBradley C Leibovich
Jan 27, 2011·Current Problems in Diagnostic Radiology·Jonathan W CurrieKenneth S Lee
Mar 18, 2011·Journal of Computer Assisted Tomography·Atul B ShinagareAnnick D Van den Abbeele
Jun 21, 2011·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal
Oct 5, 2011·CA: a Cancer Journal for Clinicians·Carol DeSantisAhmedin Jemal

❮ Previous
Next ❯

Citations

Sep 23, 2014·BMJ Case Reports·Kaouther Ben AbdelghaniLeith Zakraoui
Apr 7, 2020·Ophthalmic Plastic and Reconstructive Surgery·Alexandra J Van BrummenMatthew Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Australasian Radiology
Nevzat KarabulutCanan Akyüz
Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes
F K Ontell, A Greenspan
© 2021 Meta ULC. All rights reserved