PMID: 8581526Jan 1, 1995Paper

Scoliosis and lung function in spinal muscular atrophy

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
D RobinsonJ L Barrie

Abstract

The notes and radiographs of 43 patients with a confirmed diagnosis of spinal muscular atrophy were reviewed. A significant inverse linear relationship between the severity of scoliosis and the percentage of predicted vital capacity and peak flow was found. The patients who stood had a significantly better lung function than patients who were confined to a wheelchair, and their scoliosis deteriorated significantly more slowly. Sixteen patients underwent surgical spinal stabilisation, 4 with Harrington instrumentation and 12 with segmental spinal instrumentation, at an average age of 12 years and 11 months. The average curve correction achieved was 40%. The decline in lung function seen pre-operatively was not only reversed, but a significant improvement was found at final follow-up.

References

Mar 1, 1978·Archives of Disease in Childhood·G P HoskingR H Edwards
Dec 1, 1978·Developmental Medicine and Child Neurology·S G Benady
Nov 1, 1992·The Journal of Bone and Joint Surgery. British Volume·J B Williamson, C S Galasko
Mar 1, 1992·The Journal of Bone and Joint Surgery. British Volume·C S GalaskoP Morris
Aug 1, 1989·Developmental Medicine and Child Neurology·L MerliniR Savini
Apr 1, 1989·Journal of Child Neurology·E RodilloV Dubowitz
Feb 1, 1986·Archives of Disease in Childhood·C M Noble-JamiesonM Silverman
Jun 1, 1973·Clinical Orthopaedics and Related Research·C VauzelleP Jouvinroux
Oct 1, 1974·Developmental Medicine and Child Neurology·V Dubowitz
Nov 1, 1970·Journal of the Neurological Sciences·T NambaD Grob
Jul 1, 1983·Journal of Pediatric Orthopedics·L T KurzJ Leach
Jan 1, 1981·The Journal of Bone and Joint Surgery. British Volume·G A EvansB S Russman
Jan 1, 1995·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·C S GalaskoC M Delaney
Mar 1, 1965·The American Review of Respiratory Disease·N G HEPPERW S FOWLER

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Citations

Jul 19, 2005·Journal of Rehabilitation Medicine·Imelda J M de Groot, Luc P de Witte
Oct 12, 2012·Archives of Orthopaedic and Trauma Surgery·Albert FujakJürgen Forst
Nov 4, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Hitesh N ModiJae-Hyuk Yang
May 16, 2013·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Sonia KhiraniBrigitte Fauroux
Oct 14, 2010·Disability and Rehabilitation. Assistive Technology·Albert FujakJürgen Forst
May 9, 2014·Chest·Leanne M GauldPeter D Sly
Nov 10, 2012·Physical Medicine and Rehabilitation Clinics of North America·Nanette C JoycePaula R Clemens
Apr 21, 2012·Lancet Neurology·Eugenio MercuriSusan T Iannaccone
Nov 25, 2003·Journal of Paediatrics and Child Health·S Y ChngD Y Goh
Jun 5, 2012·The Journal of the American Academy of Orthopaedic Surgeons·Addisu MesfinArabella I Leet
Dec 2, 2014·Paediatric Respiratory Reviews·Oscar Henry Mayer
Nov 4, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Shih-Hsiang ChouYen-Mou Lu
Aug 10, 2017·Yonsei Medical Journal·Heewon HwangYoung Chul Choi
Apr 29, 2020·Clinical Spine Surgery : a Spine Publication·Po-Chih ShenShih-Hsiang Chou
Nov 20, 2016·Journal of Neuromuscular Diseases·Michela CatterucciaSusana Quijano-Roy
Nov 9, 2020·BMC Musculoskeletal Disorders·Agnieszka StępieńMaria Jędrzejowska
Feb 3, 2007·The Journal of Bone and Joint Surgery. American Volume·Daniel J Sucato

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