Scoliosis in cystic fibrosis: is it idiopathic?

Spine
Naresh KumarR A Dickson

Abstract

This is a retrospective study of all the patients registered with the Yorkshire Regional Cystic Fibrosis unit from 1982 to 1997. Of the 316 patients, there were 184 adults (age 17 years and above) and 132 children (age 0-6 years). This study was aimed at determining the prevalence of scoliosis in people with cystic fibrosis and describes the characteristics and progression of scoliosis in these patients and highlights predictive factors, which account for high prevalence of scoliosis in this condition. Two previous North American studies (1978 and 1982) have indicated a high prevalence of scoliosis in patients with cystic fibrosis. The patients were divided into 3 groups based on their chronologic age as on January 1998. Chest, abdomen, and whole spine radiographs were studied for the presence of any spinal deformity, and measurements were made using the Oxford Cobbmeter (Oxford Metrics). The extent, apex, and the side of the curves were described. The disease-specific scores, ie, Chrispin-Norman score (score for radiologic severity of lung disease) and Shwachman score (score for general condition), were noted from the patient follow-up database maintained by the Regional Cystic Fibrosis Unit. Multiple linear regression analysi...Continue Reading

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Citations

Jun 14, 2005·Bioorganic & Medicinal Chemistry Letters·Manish DixitAtul Goel
May 17, 2006·Pediatric Pulmonology·Gaudenz M HafenPhilip J Robinson
Jul 25, 2012·Pediatric Pulmonology·Valentina FainardiA Bush
Jul 15, 2016·Case Reports in Orthopedics·George I MataliotakisAndrew Fall
Sep 28, 2016·Journal of Cardiopulmonary Rehabilitation and Prevention·Annemarie L LeeDina Brooks
May 17, 2019·Case Reports in Pediatrics·Lauren M CastnerManuel Arteta
May 21, 2020·Naunyn-Schmiedeberg's Archives of Pharmacology·M S Abdel-BakkyA S Saad
Apr 1, 2020·The Cochrane Database of Systematic Reviews·Victor Hb OliveiraPatricia Angelica Ms Nogueira
May 28, 2021·Orthopedics·Mark J LambrechtsTheodore J Choma

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