SCORE2 Report 5: Vision-Related Function in Patients With Macular Edema Secondary to Central Retinal or Hemiretinal Vein Occlusion.

American Journal of Ophthalmology
Ingrid U ScottSCORE2 Investigator Group

Abstract

To describe baseline vision-related function, measured with the National Eye Institute Visual Function Questionnaire (NEI VFQ-25), in patients with macular edema secondary to central retinal vein occlusion (CRVO) or hemiretinal vein occlusion (HRVO) in the Study of COmparative Treatments for REtinal Vein Occlusion 2 (SCORE2); evaluate the baseline relationship between NEI VFQ-25 scores with visual acuity letter score (VALS) and central retinal thickness; and compare baseline NEI VFQ-25 scores in SCORE2 participants with those in normal-vision reference populations and patients in other retinal vein occlusion trials. Multicenter, noninferiority randomized controlled trial. SCORE2 was designed to assess whether intravitreal bevacizumab is noninferior to intravitreal aflibercept for treatment of decreased vision attributable to macular edema owing to CRVO or HRVO. SCORE2 enrolled 362 participants, including 305 with CRVO and 57 with HRVO. Analyses were of cross-sectional baseline data. The main outcome measures were baseline NEI VFQ-25 composite and subscale scores. SCORE2 participants' baseline NEI VFQ-25 composite and subscale scores are significantly lower compared with 3 normal-vision reference populations (P < .01; except for...Continue Reading

References

Feb 22, 1997·BMJ : British Medical Journal·J M Bland, D G Altman
Dec 22, 1999·Archives of Ophthalmology·M LinderE Weis
Jul 27, 2001·Archives of Ophthalmology·C M MangioneUNKNOWN National Eye Institute Visual Function Questionnaire Field Test Investigators
Feb 14, 2003·Archives of Ophthalmology·Traci E ClemonsUNKNOWN Age-Related Eye Disease Study Research Group
Mar 1, 2005·American Journal of Ophthalmology·Gilles H BerdeauxBenoit Arnould
Oct 22, 2013·JAMA : the Journal of the American Medical Association·UNKNOWN World Medical Association
Nov 20, 2016·Ophthalmology·Ingrid U ScottUNKNOWN SCORE2 Investigator Group
May 12, 2017·JAMA : the Journal of the American Medical Association·Ingrid U ScottUNKNOWN SCORE2 Investigator Group

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Citations

Jan 11, 2020·Asia-Pacific Journal of Ophthalmology·Kimberly SpoonerAndrew Chang
Jan 29, 2020·Asia-Pacific Journal of Ophthalmology·Kimberly SpoonerAndrew Chang
Mar 9, 2021·Seminars in Ophthalmology·Alexandros ChatzirallisIrini Chatziralli

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