Scoring the best deal: Quantity discounts and street price variation of diverted oxycodone and oxymorphone

Pharmacoepidemiology and Drug Safety
Jacob A LebinRichard C Dart

Abstract

Diverted prescription opioids are significant contributors to drug overdose mortality. Street price has been suggested as an economic metric of the diverted prescription opioid black market. This study examined variables that may influence the street price of diverted oxycodone and oxymorphone. A cross-sectional study was conducted utilizing data from the previously validated, crowdsourcing website StreetRx. Street price reports of selected oxycodone and oxymorphone products, between August 22, 2014 and June 30, 2016, were considered for analysis. Geometric means and 95% confidence intervals were calculated comparing prices per milligram of drug in US dollars. Univariate and multivariable regressions were used to examine the influence of dosage strength, drug formulation, and bulk purchasing on street price. A total of 5611 oxycodone and 1420 oxymorphone reports were analyzed. Across various dosages and formulations, geometric mean prices per milligram ranged between $0.12 and $1.07 for oxycodone and $0.73 and $2.90 for oxymorphone. For a 2-fold increase in dosage strength, there is a 24.0% (95% CI: -28.1%, -19.6%, P < 0.001) and a 22.5% (95% CI: -24.2%, -20.8%, P < 0.001) decrease on average in price per milligram for oxycodon...Continue Reading

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Citations

Oct 24, 2020·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Stevan Geoffrey SevertsonRichard C Dart
Nov 7, 2020·Drug and Alcohol Dependence·Janetta L IwanickiRichard C Dart
Nov 24, 2020·The American Journal of Drug and Alcohol Abuse·Kirsten Elin SmithErin Winston

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