Scratching behavior in various strains of mice

Skin Pharmacology and Applied Skin Physiology
N InagakiH Nagai

Abstract

Scratching behavior was induced in 12 strains of mice and the frequency was compared. An injection of histamine at a dose of 50 nmol induced frequent scratching behavior only in ICR mice, although the same dose of serotonin induced frequent scratching behavior in all strains of mice except for A/J. Histamine (10 nmol), serotonin (1 nmol), substance P (50 nmol) and passive cutaneous anaphylaxis induced significant vascular permeability increase in BALB/c, ICR, ddY and NC/Nga mice. These four stimuli also induced frequent scratching behavior in ICR mice. However, they failed to induce substantial increase in the incidence of scratching in the other three strains, except for ddY, which exhibited a slight but significant increase against substance P injection. These results suggest that the ICR mouse is a good responder for scratching behavior against various stimuli, especially against histamine. Thus ICR mice may be suitable for studying mediators and/or mechanisms for itching.

Citations

Jun 16, 2010·Archives of Dermatological Research·Yasutomo FujiiShoji Takakura
Jun 27, 2009·Archives of Pharmacal Research·Jeong Hee JeonSeong Soo Joo
May 26, 2005·International Immunopharmacology·Maria Alejandra HossenChiaki Kamei
Jul 30, 2002·European Journal of Pharmacology·Naoki InagakiHiroichi Nagai
Oct 22, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·F A Santos, V S N Rao
May 11, 2010·Acta Pharmacologica Sinica·Hien-trung TrinhDong-hyun Kim
May 21, 2010·Journal of Neurophysiology·Junichi HachisukaMegumu Yoshimura
Jan 22, 2008·Journal of Translational Medicine·Mark J S MillerKeith A Sharkey
Sep 11, 2007·Biological & Pharmaceutical Bulletin·Shuishi JiangChiaki Kamei
Jan 13, 2015·Immunopharmacology and Immunotoxicology·Tasuku NakasoneChiaki Kamei
Dec 31, 2015·Journal of Agricultural and Food Chemistry·Jian-Rong ZhouKazumi Yokomizo
Apr 17, 2012·Experimental Eye Research·Tsugunobu AndohYasushi Kuraishi
May 1, 2012·Clinics in Liver Disease·Chalermrat Bunchorntavakul, K Rajender Reddy
Aug 4, 2011·Clinics and Research in Hepatology and Gastroenterology·Andreas E KremerUlrich Beuers
May 23, 2015·Biomolecules & Therapeutics·Kyungho Park
Mar 8, 2016·European Journal of Pharmacology·Tasuku NakasoneChiaki Kamei
Mar 3, 2009·European Journal of Pharmacology·Yoshiyuki NakanoChiaki Kamei
Apr 6, 2012·The Journal of Investigative Dermatology·Erika Yamamoto-KasaiTakeshi Yoshioka
Aug 7, 2009·The Journal of Investigative Dermatology·Tsugunobu AndohYasushi Kuraishi
May 28, 2010·The Journal of Investigative Dermatology·Simarna KaurMichael D Southall
Jan 30, 2004·The British Journal of Dermatology·K OritoH Matsuda
Sep 21, 2011·Experimental Dermatology·Robert H LaMotteParul Sikand
Dec 8, 2004·Life Sciences·Yuki HashimotoShiro Nakaike
Aug 18, 2004·International Immunopharmacology·Yoshifumi ShinmeiChiaki Kamei
Aug 22, 2006·International Immunopharmacology·Yuhki UedaChiaki Kamei
Jun 19, 2009·The Journal of Investigative Dermatology·Ikuko NumataSetsuya Aiba
Jun 6, 2003·The Journal of Investigative Dermatology·Swarna Ekanayake MudiyanselageJens J Thiele
May 11, 2015·Pharmacology, Biochemistry, and Behavior·Arash ForoutanAhmad Reza Dehpour
Mar 14, 2007·Journal of Dermatological Science·Mitsutoshi TominagaKenji Takamori
Sep 16, 2008·Pain·Steven G Shimada, Robert H LaMotte

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.