Screening and management of osteoporosis in breast cancer patients on aromatase inhibitors

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners
Kelli Gibson, Cindy L O'Bryant

Abstract

Breast cancer patients are at an increased risk of osteoporosis due to age, cancer, chemotherapy, and aromatase inhibitor therapy. This retrospective review determined if patients treated with aromatase inhibitors received appropriate screening and management for osteoporosis. University of Colorado Cancer Center breast cancer patients treated with aromatase inhibitor therapy during July 2005 through July 2006 were studied. Data was collected for each patient from the time of breast cancer diagnosis up to April 2007. The study endpoints included (1) appropriate screening for osteoporosis, (2) incidence of osteoporosis diagnosis, and (3) initiation of appropriate drug therapy for bone loss. Appropriate management was defined as adherence to the 2003 American Society of Clinical Oncology guidelines for bone health issues in women with breast cancer. Of the 54 patients included in this study, 12 (22.2%) had no DEXA scans documented, 22 (40.7%) patients received a baseline DEXA scan and 8 (14.8%) patients received baseline and yearly DEXA scans. During the study timeline, 26 (48%) patients were diagnosed with osteopenia and 4 (7%) patients were diagnosed with osteoporosis. Forty-one (75.9%) patients received calcium and vitamin D t...Continue Reading

References

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Citations

Oct 23, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R RizzoliUNKNOWN International Osteoporosis Foundation Committee of Scientific Advisors Working Group on Cancer-Induced Bone Disease
Feb 1, 2013·Journal of Women's Health·Leslie SpanglerDenise M Boudreau
Sep 9, 2015·Internal Medicine Journal·R RobertsB Koczwara
Oct 27, 2015·Journal of Cancer Survivorship : Research and Practice·Jude K A des BordesMaria A Lopez-Olivo
Jul 14, 2016·Journal of Oncology Practice·Jingyan YangDawn L Hershman
Apr 29, 2014·Hospital Practice·Derek S Tsang, Shabbir M Alibhai
Jan 24, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Huifang LuMaria Suarez-Almazor

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