Screening and surveillance CT abdomen/pelvis for metastases in patients with soft-tissue sarcoma of the extremity

Bone & Joint Research
M J ThompsonW Foster

Abstract

The clinical utility of routine cross sectional imaging of the abdomen and pelvis in the screening and surveillance of patients with primary soft-tissue sarcoma of the extremities for metastatic disease is controversial, based on its questionable yield paired with concerns regarding the risks of radiation exposure, cost, and morbidity resulting from false positive findings. Through retrospective review of 140 patients of all ages (mean 53 years; 2 to 88) diagnosed with soft-tissue sarcoma of the extremity with a mean follow-up of 33 months (0 to 291), we sought to determine the overall incidence of isolated abdominopelvic metastases, their temporal relationship to chest involvement, the rate of false positives, and to identify disparate rates of metastases based on sarcoma subtype. A total of four patients (2.9%) exhibited isolated abdominopelvic metastatic disease during the surveillance period. In all cases of concomitant chest and abdominopelvic disease, chest involvement preceded abominopelvic involvement. There was a significant false positive rate requiring invasive workup. In the setting of a relative paucity of evidence concerning a rare disease process and in difference to recently published investigations, we add a cl...Continue Reading

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Citations

May 22, 2018·The Journal of the American Academy of Orthopaedic Surgeons·Robert J Steffner, Eugene S Jang
Oct 28, 2019·The Journal of the American Academy of Orthopaedic Surgeons·Cara A CiprianoWakenda Tyler
Jan 24, 2020·Journal of Surgical Oncology·Ranyell M S S B SpencerAdemar Lopes
Mar 7, 2020·World Journal of Clinical Oncology·Maria Anna SmolleGerwin Alexander Bernhardt
Jul 15, 2020·Current Medical Imaging·Shinji TsukamotoCostantino Errani

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