Screening for acquired cystic kidney disease: a decision analytic perspective

Kidney International
F P SarasinK B Meyer

Abstract

Acquired cystic kidney disease (ACKD) increases the risk of renal malignancy, and many authors suggest routine screening of dialysis patients for ACKD and renal tumors. However, they have defined neither the target population, the optimal screening strategy, the magnitude of its benefit, nor its risk. We used decision analysis to evaluate strategies of performing either computed tomography (CT) or ultrasound every three years on all dialysis patients and annually on patients found to have cysts. We compared these strategies to a strategy of seeking cysts and cancer only if these are clinically suspected. The baseline analysis shows that both CT and ultrasound may decrease cancer deaths by half for patients with a life expectancy of 25 years. Screening for ACKD offers these patients as much as a 1.6 year gain in life expectancy. However, for the majority of patients beginning renal replacement therapy, age or comorbid disease substantially limits life expectancy. For such patients, the gain in life expectancy from an ACKD screening program is measured in days. Sensitivity analyses show that the benefit of screening depends on the rate of malignant transformation, which needs better definition. The gain in life expectancy does no...Continue Reading

References

Jun 1, 1975·American Journal of Surgery·A J MatasC M Kjellstrand
Oct 1, 1992·Journal of the American Society of Nephrology : JASN·J E SiegelM C Weinstein
Aug 15, 1992·Annals of Internal Medicine·W M McClellanR A Gutman
Mar 1, 1991·AJR. American Journal of Roentgenology·E LevineL H Wetzel
Dec 1, 1991·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Y H LienG P Schröter
Apr 1, 1991·British Journal of Urology·J F BrennanM B Siroky
Aug 1, 1990·Annals of Internal Medicine·D M Eddy
May 1, 1990·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·P W Eggers
Sep 1, 1990·Annals of Internal Medicine·D M Eddy
May 1, 1990·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A J CollinsP Keshaviah
Aug 1, 1990·The Journal of Urology·P Hermanek, K M Schrott
Mar 1, 1989·Radiology·S J SmithB N Raghavendra
Oct 1, 1989·AJR. American Journal of Roentgenology·A J TaylorW D Foley
Jan 1, 1989·Urologic Radiology·H J Mindell
Aug 1, 1989·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·F K PortV M Hawthorne
Jan 1, 1989·American Journal of Nephrology·L R MillerM H Kutner
Mar 1, 1988·Radiology·M A AmendolaJ E Tomaszewski
Nov 1, 1986·Kidney International·N NarasimhanW M Bennett
Jan 29, 1987·The New England Journal of Medicine·S G Pauker, J P Kassirer
Feb 1, 1987·Annals of Internal Medicine·J P KassirerS G Pauker
May 1, 1987·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A KatzD G Oreopoulos
Aug 1, 1986·The Journal of Urology·J D Maldazys, J B deKernion
Jan 1, 1987·Medical Decision Making : an International Journal of the Society for Medical Decision Making·M H EckmanS G Pauker
Feb 1, 1987·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M L MacDougallT B Wiegmann
Aug 1, 1985·Urology·I Ishikawa
Aug 1, 1985·Kidney International·J J Grantham, E Levine
Apr 1, 1986·Urology·M GolimbuP Morales
Nov 1, 1985·The American Journal of Medicine·J J GehrigR S Swenson
Oct 1, 1985·British Journal of Cancer·S KoscielnyA J Valleron
Oct 1, 1968·American Journal of Clinical Pathology·S Kay
Aug 1, 1973·British Journal of Urology·I LissoosA M Meijers
Mar 1, 1969·The Journal of Urology·C J RobsonW Anderson
May 1, 1984·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·W Weiss
Jan 1, 1984·AJR. American Journal of Roentgenology·E LevineB P Krohn
May 1, 1984·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·K D Gardner, A P Evan
Dec 17, 1983·British Medical Journal·P J RatcliffeD O Oliver

❮ Previous
Next ❯

Citations

Feb 13, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·F P Sarasin
Feb 21, 2008·Nature Clinical Practice. Nephrology·Devasmita Choudhury, Cynthia Luna-Salazar
Aug 20, 2011·Seminars in Dialysis·Swathi Singanamala, Ursula C Brewster
Mar 6, 2013·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Kazushige SakaguchiSusumu Horiuchi
Sep 29, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S TakebayashiS Matsubara
Jan 25, 2005·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Isao IshikawaTatsuyuki Kakuma
Oct 23, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Nov 21, 2007·Hemodialysis International·Ann E Moore, Dean A Kujubu
Aug 1, 1997·The Urologic Clinics of North America·E LevineJ C Barth
May 26, 2017·Seminars in Dialysis·Frederic Rahbari-Oskoui, William Charles O'Neill
Feb 6, 2018·Nature Reviews. Nephrology·Susie L Hu, Robert H Weiss
Apr 4, 2018·World Journal of Urology·Sabrina H RossiGrant D Stewart
Sep 28, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Chi Yuen Cheung, Sydney Chi Wai Tang
Nov 6, 2018·Nephrology·Chi Yuen Cheung, Sydney C W Tang
Aug 19, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Jean L Holley
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·John D Scandling
Mar 14, 2000·The Korean Journal of Internal Medicine·D H LeeT H Lee
Oct 3, 2000·Seminars in Dialysis·J Tantravahi, T I Steinman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Related Papers

Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
I IshikawaTatsuyuki Kakuma
© 2021 Meta ULC. All rights reserved