PMID: 11922382Apr 2, 2002Paper

Screening for amblyopia in preschool children: results of a population-based, randomised controlled trial. ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood

Ophthalmic Epidemiology
C WilliamsALSPAC Study Team

Abstract

The rationale for preschool vision screening programmes has recently been questioned. Evidence about the effects of early treatment is needed, but it is not known how early the target conditions can reliably be detected. In this study, an intensive programme comprising several different screening methods, used at different ages up to 37 months, was compared with the usual practice of visual surveillance and ad hoc referrals. Two groups were randomly selected from children in a population birth cohort study. The control group (n = 1461) received visual surveillance only. The intervention group (n = 2029) was offered in addition a programme of regular visual assessments by orthoptists testing visual acuity, ocular alignment, stereopsis and non-cycloplegic photorefraction. The intervention group programme yielded more children with amblyopia (1.6% vs. 0.5%, p < 0.01), and was more specific (95% vs. 92%, p < 0.01), than the control programme. The individual components of the intervention programme were compared. The cover test and visual acuity tests were poorly sensitive until the children were 37 months, but were always >99% specific. Photorefraction was more sensitive than acuity testing at all ages below 37 months, with specifi...Continue Reading

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Citations

Jun 6, 2009·Paediatric and Perinatal Epidemiology·Jean Golding
Mar 4, 2006·Strabismus·Cathy Williams, Richard Harrad
Jul 22, 2010·Child: Care, Health and Development·M MathersM Wright
Mar 23, 2011·International Ophthalmology·Evgenia Kanonidou
Jul 18, 2009·BMC Ophthalmology·Christine SchmuckerJos Kleijnen
Jun 30, 2009·Applied Health Economics and Health Policy·Jonathan KarnonKevin Smith
May 23, 2020·Ophthalmic Epidemiology·Coralie HemptinneDemet Yüksel
Aug 12, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christine SchmuckerJos Kleijnen
Sep 27, 2012·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Julie Anne LittleKathryn J Saunders
Nov 7, 2017·The Cochrane Database of Systematic Reviews·Sarah HullAnnegret Dahlmann-Noor
Jun 16, 2018·Visual Neuroscience·David Hunter, Susan Cotter
Jun 27, 2018·Indian Journal of Ophthalmology·Damaris MagdaleneKrati Gupta
Jun 6, 2003·Clinical & Experimental Ophthalmology·Kathryn RosePaul Mitchell
Feb 15, 2007·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Janette AtkinsonShirley Anker
Jun 27, 2007·Developmental Medicine and Child Neurology·Lisbeth Sandfeld NielsenHanne Jensen
Nov 29, 2017·Strabismus·Frea SlootHuibert Jan Simonsz
Aug 26, 2006·Current Opinion in Ophthalmology·Jean E Ramsey, Geoffrey E Bradford
May 23, 2019·Journal of Pediatric Ophthalmology and Strabismus·Howard FreedmanJ Timothy Diegel
Oct 26, 2016·Journal of Acupuncture and Meridian Studies·Marzio Vanzini, Michele Gallamini
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Sep 15, 2007·American Journal of Ophthalmology·Hooi Kuan TanUNKNOWN European Multicentre Study on Congenital Toxoplasmosis (EMSCOT)
Sep 10, 2021·Ophthalmology and Therapy·Eileen E BirchJingyun Wang
Mar 2, 2011·Vision Research·Oliver Braddick, Janette Atkinson
Feb 13, 2013·Pediatrics·Susannah Q LongmuirWilliam E Scott
Feb 2, 2011·Pediatrics·Roger ChouChristina Bougatsos

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