PMID: 2109544May 1, 1990Paper

Screening for Chlamydia trachomatis in adolescent males: a cost-based decision analysis

American Journal of Public Health
A G Randolph, A E Washington

Abstract

To evaluate the cost and benefits of screening tests for Chlamydia trachomatis in adolescent males, we developed a decision analysis model and compared the leukocyte esterase urine dipstick test with culture, with direct-smear fluorescent antibody (DFA), and with the option of no screening (no treatment). The leukocyte esterase test has the lowest average cost-per-cure ($51) compared with direct-smear fluorescent antibody ($192) and culture ($414). Compared with the DFA, we estimate that the leukocyte esterase test saves over $9,727 per cohort of 1,000 sexually active adolescent males screened. Sensitivity analyses show the leukocyte esterase test results in a lower cost-per-cure and lower overall costs (per cohort) than culture and direct-smear fluorescent antibody at any prevalence of C. trachomatis infection, and lower overall costs (per cohort) than no screening at prevalences above 21 percent.

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Citations

Sep 21, 2000·Journal of Reproductive Immunology·K W Beagley, P Timms
Jul 1, 1993·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·J JohnsonL D Cowan
Jan 26, 1999·Sexually Transmitted Diseases·H Zimmerman-RogersH A White
Feb 5, 2003·Sexually Transmitted Diseases·Rachel H S GinocchioJeanne M Marrazzo
Jan 27, 2004·Sexually Transmitted Diseases·Diane R BlakeThomas C Quinn
Jun 25, 2005·Sexually Transmitted Diseases·Julia E AledortSue J Goldie
Sep 28, 2006·Sexually Transmitted Diseases·Thomas L Gift, Chantelle J Owens
Jun 4, 2008·Sexually Transmitted Diseases·Thomas L GiftJeanne M Marrazzo
Jan 1, 1992·The Journal of School Health·D Cora-BrambleB Sklarew
May 30, 2006·Sexually Transmitted Infections·T E RobertsUNKNOWN Chlamydia Screening Studies (ClaSS) Group
Sep 20, 2002·Sexually Transmitted Infections·J DebattistaM Mortlock
May 1, 1990·American Journal of Public Health·E R Alexander
Mar 1, 1993·Journal of American College Health : J of ACH·D G FerrisM Litaker
Apr 4, 2006·Obstetrics and Gynecology·Kyle T BernsteinEmily J Erbelding
Nov 23, 2006·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Jeanelle SheederStephen Scott
Sep 21, 2005·Journal of Pediatric and Adolescent Gynecology·Catherine Stevens-Simon, Jeanelle Sheeder
Oct 18, 2012·Journal of Policy Analysis and Management : [the Journal of the Association for Public Policy Analysis and Management]·Leonard M Lopoo, Kerri M Raissian
Oct 1, 1992·Applied Economics·Y Georgellis, H J Wall
Jan 13, 2012·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Michael Petros
Jun 1, 1991·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·M J Werner, F M Biro

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