Screening for congenital malformations by ultrasonography in the general population of pregnant women: factors affecting the efficacy

Acta Obstetricia Et Gynecologica Scandinavica
Ann TaborBeth Lilja Pedersen

Abstract

To assess whether the efficacy of screening for fetal malformations is affected by patient-, staff-, team- or work environment-related factors. A prospective cohort study was carried out at a Danish university hospital with 4000 deliveries per year. In total, 7963 fetuses were examined by midtrimester ultrasound scan during 1997 and 1998. The infants were followed up to the age of at least 1 year. The main outcome measures were the detection rate (DR) of fetal abnormalities in relation to patient factors, staff factors, team and work environment factors. Significant malformations were detected in 100 fetuses or infants, corresponding to an incidence of 1.3%. The prenatal DR was 60%. High maternal body mass index (BMI) was associated with a lower DR, while the presence of twins, the gestational age at time of screening and the sonographer's level of experience were not. Fetuses with a prenatally undetected malformation were more often examined by more than one sonographer than fetuses without congenital malformations. Workload or monotony did not seem to affect the efficacy of screening. There was a trend towards a lower detection rate at midday and when most of the staff were at work. Some team and work environment factors that...Continue Reading

References

Mar 1, 1992·British Journal of Obstetrics and Gynaecology·G K Sharland, L D Allan
Dec 1, 1994·American Journal of Obstetrics and Gynecology·L F GonçalvesJ M Piper
Nov 1, 1993·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·G R DeVoreL D Platt
Nov 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M A RusticoG Mandruzzato
Nov 1, 1996·American Journal of Obstetrics and Gynecology·D W SkupskiL B McCullough
Aug 24, 1999·American Journal of Obstetrics and Gynecology·H GrandjeanS Levi
Sep 24, 1999·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·P SchwärzlerY Ville
Mar 17, 2000·BMJ : British Medical Journal·J Reason
Feb 24, 2001·Acta Obstetricia Et Gynecologica Scandinavica·E Garne, UNKNOWN Eurocat Working Group

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Citations

Dec 17, 2008·Women's Health·Murizah M Zain, Robert J Norman
Sep 17, 2008·Reproductive Health Matters·Hilmar H BijmaHajo I J Wildschut
Aug 21, 2012·BJOG : an International Journal of Obstetrics and Gynaecology·K E BestJ Rankin
Aug 23, 2012·Pediatric Pulmonology·Gregory J ReddingJeffrey R Avansino
Oct 2, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C StruksnaesC Vogt
Oct 19, 2004·Acta Obstetricia Et Gynecologica Scandinavica·Kirsten Riis AndreasenAnne Louise Schantz

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