Screening for esophagitis and Barrett's esophagus with wireless esophageal capsule endoscopy: a multicenter prospective trial in patients with reflux symptoms

The American Journal of Gastroenterology
Jean-Paul GalmichePhilippe Ducrotté

Abstract

Esophageal capsule endoscopy (ECE) is a new technology that allows noninvasive investigation of the esophagus. Our aim was to evaluate prospectively the diagnostic yield of ECE in patients with chronic reflux symptoms. Eighty-nine patients (40 men, mean age 54 yr) referred to five endoscopic centers for esophagogastroduodenoscopy (EGD) were enrolled. Patients first underwent ECE, then EGD; endoscopists who performed the EGD were blind to the ECE data that were interpreted separately by two independent readers. The Los Angeles, Prague, and Montreal classification systems were used to describe endoscopic findings. Seventy-seven patients completed the study. Esophagitis and endoscopically suspected esophageal metaplasia (ESEM) were present in 24 and 10 patients, respectively. Columnar lining was histologically confirmed in seven patients (3 with specialized intestinal metaplasia and 4 with gastric metaplasia). The kappa values for interobserver agreement regarding the diagnosis of esophagitis and ESEM were 0.67 (0.49-0.85) and 0.49 (0.17-0.81), respectively. The diagnostic yields of ECE to detect esophagitis and ESEM were as follows: sensitivity 79% and 60%, specificity 94% and 100%, positive predictive value (PPV) 83% and 100%, n...Continue Reading

References

Jan 31, 2002·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·E M Quigley, J K DiBaise
Nov 15, 2003·Journal of Clinical Epidemiology·J A Knottnerus, J W Muris
Jul 6, 2004·Gastroenterology·Prateek SharmaUNKNOWN AGA Chicago Workshop
Aug 19, 2004·European Journal of Gastroenterology & Hepatology·Stanislas Bruley des Varannes
Sep 24, 2004·Digestive Diseases·Jean Paul Galmiche, Kate Stephenson
Dec 1, 2004·Alimentary Pharmacology & Therapeutics·R EliakimG M Eisen
Dec 14, 2005·Gastroenterology·Jukka RonkainenLars Agréus
Aug 9, 2006·European Journal of Gastroenterology & Hepatology·Andrés Sánchez-YagüeJuan Manuel Herrerías-Gutiérrez
Aug 25, 2006·The American Journal of Gastroenterology·Nimish VakilUNKNOWN Global Consensus Group
Mar 21, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Joel H RubensteinGlenn M Eisen
Mar 21, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Lauren Gerson, Otto S Lin

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Citations

Apr 25, 2014·Gastroenterology Report·Raja Shekhar Sappati Biyyani, Amithab Chak
Oct 12, 2013·World Journal of Gastroenterology : WJG·Ashish ShahDenise Kalmaz
Oct 22, 2015·Gastroenterology Report·Ajaypal Singh, Amitabh Chak
Jul 28, 2009·Gastrointestinal Endoscopy·William Hale
Aug 15, 2009·Gastroentérologie Clinique Et Biologique·S Sacher-HuvelinJ-P Galmiche
Mar 10, 2009·Lancet·Nicholas J Shaheen, Joel E Richter
Feb 5, 2009·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·G NakosC Mavrogiannis
May 13, 2009·Nature Reviews. Gastroenterology & Hepatology·Andrea MogliaAlfred Cuschieri
Jul 2, 2009·Journal of Clinical Gastroenterology·Matti Waterman, Ian M Gralnek
Aug 8, 2009·Journal of Clinical Gastroenterology·Christopher M White, Meredith L Kilgore
Jun 3, 2010·Nature Reviews. Gastroenterology & Hepatology·Rami J Badreddine, Kenneth K Wang
Mar 21, 2012·Nature Reviews. Clinical Oncology·Pierre Lao-Sirieix, Rebecca C Fitzgerald
Sep 7, 2011·Nature Reviews. Gastroenterology & Hepatology·Aparna Repaka, Amitabh Chak
Mar 22, 2014·Digestive Diseases and Sciences·Milli GuptaPrasad G Iyer
Nov 18, 2014·World Journal of Gastroenterology : WJG·Eduardo Redondo-CerezoJavier De Teresa
Apr 1, 2015·Frontline Gastroenterology·O J OldH Barr
Jun 15, 2011·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·D ChavalitdhamrongR Jutabha
Jul 28, 2019·Current Gastroenterology Reports·Don C Codipilly, Prasad G Iyer
Sep 12, 2014·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Naoki HosoeHaruhiko Ogata
Aug 7, 2018·Clinical Endoscopy·Junseok ParkJi Hyun Kim
Aug 24, 2019·Gastrointestinal Endoscopy·UNKNOWN ASGE STANDARDS OF PRACTICE COMMITTEEUNKNOWN ASGE Standards of Practice Committee Chair
Jun 4, 2019·Gastrointestinal Endoscopy·Bashar J QumseyaSachin Wani
Feb 24, 2015·Gastroenterology·Massimiliano di PietroKenneth K Wang

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