Screening for gastric cancer with magnetically controlled capsule gastroscopy in asymptomatic individuals

Gastrointestinal Endoscopy
An-Jing ZhaoZhuan Liao

Abstract

Gastric cancer (GC) is the fourth most common cancer and the fourth leading cause of cancer death worldwide. In some Asian countries, screening EGD has greatly improved the survival rate. However, patients' discomfort and the need for sedation may limit adherence to screening programs. Previous studies have shown good tolerance and good agreement of magnetically controlled capsule gastroscopy (MCCG) with EGD. This study was designed to assess the application of MCCG in GC detection in an asymptomatic population. In this observational cohort study, 3182 asymptomatic individuals undergoing MCCG in 99 participating medical examination centers from April to December 2016 were enrolled. Patients with ulcers and suspected malignancies were referred for gastroscopy and biopsy. The detection rate of GC and focal lesions were used to explore the application of MCCG in asymptomatic individuals. Seven patients (0.22%) were diagnosed with GC among the enrolled 3182 individuals, accounting for 0.74% (7/948) in patients over 50 years. No gender disparity was observed. EGD and biopsy confirmed adenocarcinoma in all cases of suspected malignancy. Benign polyps, gastric ulcers, and submucosal tumors were found in 10.4%, 4.9%, and 3.6% of patien...Continue Reading

Citations

Feb 13, 2019·Journal of Pediatric Gastroenterology and Nutrition·Zhujun GuHaifeng Liu
Sep 5, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Hua-Sheng LaiSi-de Liu
Apr 25, 2020·Annals of the Royal College of Surgeons of England·X-Y GeX Jiang
Mar 18, 2020·Journal of Gastroenterology and Hepatology·Leonardo Henry EusebiRocco Maurizio Zagari
Sep 12, 2020·Molecular Oncology·Yubo TangRebecca Richards-Kortum
Dec 19, 2018·Digestive Diseases and Sciences·Yuan-Chen WangZhuan Liao
Aug 17, 2019·Soft Robotics·Donghoon SonMetin Sitti
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Oct 29, 2020·Expert Review of Gastroenterology & Hepatology·Stefania Chetcuti Zammit, Reena Sidhu
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Mar 4, 2021·Endoscopy International Open·Zhuan LiaoUNKNOWN Capsule Endoscopy Group of the Chinese Society of Digestive Endoscopy

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