Screening for major depressive disorder with the Patient Health Questionnaire (PHQ-9 and PHQ-2) in an outpatient clinic staffed by primary care physicians in Japan: a case control study

PloS One
Keiko SuzukiToshikatsu Okumura

Abstract

The Patient Health Questionnaire (PHQ-9) is a self-report questionnaire commonly used to screen for depression, with ≥8-11 generally recommended as the cut-off. In Japan, studies of the validity of the PHQ-9 and PHQ-2 have been limited. In this study, we examined the utility of the PHQ-9 and PHQ-2 at an outpatient clinic in a Medical University Hospital in Japan. New consecutive outpatients were included in the study. We administered the PHQ-9 to 574 patients, and acquired complete PHQ-9 and PHQ-2 data for 521 patients. Major depressive disorders were diagnosed according to the DSM-IV-TR. Forty-two patients were diagnosed with major depressive disorders. The mean PHQ-9 (15.7) and PHQ-2 (3.8) scores of the patients with major depressive disorders were significantly higher than the scores of the patients without depression (6.0 (PHQ-9) and 1.8 (PHQ-2)). The best cut-off points for the PHQ-9 and PHQ-2 summary scores were ≥11 (sensitivity 0.76, specificity 0.81) and ≥3 (sensitivity 0.76, specificity 0.82), respectively. No relationship was observed between the age and PHQ-9 scores. The PHQ-9 and PHQ-2 were useful instruments for screening for major depressive disorders. The best cut-off point for the PHQ-9 summary score should be ≥...Continue Reading

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Citations

Mar 31, 2017·The Journal of Spinal Cord Medicine·Julia M P PoritzHerb Ames
Aug 30, 2017·Modern Rheumatology·Rosarin SruamsiriHisashi Yamanaka
Mar 16, 2016·PloS One·Zi-Wei LiuShui-Yuan Xiao
Jun 7, 2019·BioPsychoSocial Medicine·Takatoshi HirayamaKen Shimizu
Feb 9, 2021·Journal of Aging and Health·Kedar MateJinghan Zhang

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