Screening for post-miscarriage psychiatric morbidity

American Journal of Obstetrics and Gynecology
Ingrid H LokTony K H Chung

Abstract

The purpose of this study was to evaluate 12-item General Health Questionnaire (GHQ-12) in screening for psychiatric morbidity after miscarriage. A prospective cohort study was carried out involving 222 patients. Six weeks after miscarriage, the GHQ-12 was applied. Psychiatric "case" or "non-case" was diagnosed by the psychiatrist with use of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-III-R. The patients were computer randomized into Groups A or B. A receiver operating characteristic (ROC) curve was constructed for Group A. The optimal cutoff value of GHQ-12 was determined, and this value was applied to Group B. The test characteristics were assessed. Twenty-seven patients were found to be psychiatric cases. An ROC with area under curve of 0.93 (95% CI 0.87-0.99, P<.001) was constructed. The best GHQ-12 cutoff score was > or =4 in detecting psychiatric caseness. A sensitivity of 83%, specificity of 90%, positive predictive value of 50%, and negative predictive value of 98% were obtained. GHQ-12 is an effective screening tool in detecting psychiatric morbidity after miscarriage.

References

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Citations

Feb 29, 2016·Journal of Affective Disorders·Kai Sing SunEdmund Wing Wo Lam
Feb 6, 2016·Current Psychiatry Reports·Amritha Bhat, Nancy Byatt
May 1, 2010·General Hospital Psychiatry·Adrian kwan-ho ShamWinsom yau-bong Ho
Apr 6, 2007·Midwifery·Dominic T S LeeTony K H Chung
Feb 24, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Ingrid H Lok, Richard Neugebauer
Jul 14, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·G W S KongI H Lok
Jun 11, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·G W S KongI H Lok
Feb 24, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·K W S Shan Grace
Oct 3, 2017·PloS One·Kai Sing SunEdmund Wing Wo Lam
Jul 22, 2021·Neuropsychiatric Disease and Treatment·Yongfu ZhangYu Chen

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