Screening-level risk assessment of Di(2-ethylhexyl)phthalate for aquatic organisms using monitoring data in Japan.

Environmental Monitoring and Assessment
Wataru NaitoKikuo Yoshida

Abstract

Screening-level ecological risk assessments of di(2-ethylhexyl)phthalate (DEHP) for aquatic organisms in Japan were conducted using estimated statistical values based on surface water and sediment monitoring data and effect threshold values based on a large aquatic toxicity database. An alternative method is proposed to handle monitoring data that contain nondetects including multiple detection limits and to determine the statistical values of DEHP concentrations in Japanese surface waters. The No-Observed-Effect-Concentration (NOEC(water)) of DEHP for aquatic life of 77 micro g/L was determined giving equal importance to both physical effects probably caused by undissolved DEHP and to the intrinsic toxicity potentially caused by DEHP. The NOEC(sediment) of 615,000 micro g/kg was determined by the Equilibrium Partitioning (EqP) theory, conservatively assuming a threshold effect level in the water column as the water solubility of 3 micro g/L. The potential risks of DEHP in Japanese water environments were characterized simply by comparing the margin of exposure (MOE) with a specified uncertainty multiplier (UM). The MOE is expressed as the ratio of NOEC(water) or NOEC(sediment) to the expected environmental concentrations such ...Continue Reading

References

Sep 1, 1986·Archives of Environmental Contamination and Toxicology·G E CarlbergJ U Skåre
Feb 1, 1987·Bulletin of Environmental Contamination and Toxicology·P Woin, P Larsson
Jan 1, 1973·Environmental Health Perspectives·F L Mayer, H O Sanders
Feb 1, 1997·Regulatory Toxicology and Pharmacology : RTP·H J KlimischU Tillmann
Jun 1, 1994·European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics·R NilssonG M Schreuder
Jun 29, 2004·Waste Management·Hiroshi AsakuraNobutoshi Tanaka
Sep 1, 2004·Environment International·T E LewisM L Barta
Jul 29, 2005·Environmental Science & Technology·Kris Christen
May 1, 2000·Environmental Science & Technology
May 1, 1999·Environmental Science & Technology

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Citations

Feb 26, 2010·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Jan L LycheJanneche U Skaare
Jun 17, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jörg OehlmannCharles R Tyler
Apr 1, 2014·International Journal of Hygiene and Environmental Health·Hai-Xia SuiZhao-Ping Liu
Jul 16, 2015·Environmental Toxicology and Chemistry·Takashi NagaiIkuko Yoda
Jul 14, 2010·The Science of the Total Environment·Wataru NaitoYuichi Iwasaki
Nov 11, 2016·Environmental Science and Pollution Research International·Makiko IchiharaKoh-Ichi Takakura
May 13, 2018·International Journal of Environmental Research and Public Health·Ting YangYanchun Yan
Mar 3, 2015·Environmental Science & Technology·Sopheak NetBaghdad Ouddane

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