Screening of Antioxidant Activity of Gentian Lutea Root and Its Application in Oil-in-Water Emulsions

Antioxidants
Nurul Aini Mohd AzmanMaria Pilar Almajano

Abstract

Gentiana Lutea root (G. Lutea) is a medicinal herb, traditionally used as a bitter tonic in gastrointestinal ailments for improving the digestive system. The active principles of G. Lutea were found to be secoiridoid bitter compounds as well as many other active compounds causing the pharmacological effects. No study to date has yet determined the potential of G. Lutea antioxidant activity on lipid oxidation. Thus, the aim of this study was to evaluate the effects of an extract of G. Lutea on lipid oxidation during storage of an emulsion. G. Lutea extracts showed excellent antioxidant activity measured by DPPH scavenging assay and Trolox equivalent antioxidant capacity (TEAC) assays. An amount of 0.5% w/w G. Lutea lyophilise was able to inhibit lipid oxidation throughout storage (p < 0.05). A mixture of G. Lutea with 0.1% (w/w) BSA showed a good synergic effect and better antioxidant activity in the emulsion. Quantitative results of HPLC showed that G. Lutea contained secoiridoid-glycosides (gentiopiocroside and sweroside) and post column analysis displayed radical scavenging activity of G. Lutea extract towards the ABTS radical. The results from this study highlight the potential of G. Lutea as a food ingredient in the design ...Continue Reading

References

Apr 22, 1996·FEBS Letters·N J MillerC A Rice-Evans
Dec 10, 1999·Journal of Agricultural and Food Chemistry·J R MancusoE A Decker
Dec 10, 1999·Journal of Agricultural and Food Chemistry·J R MancusoE A Decker
Jun 5, 2004·Cardiovascular Drug Reviews·De-Jian JiangYuan-Jian Li
Jul 26, 2006·Journal of Asian Natural Products Research·Q-X WuY-P Shi
Oct 13, 2006·Journal of Agricultural and Food Chemistry·Terrence Madhujith, Fereidoon Shahidi
Dec 29, 2006·Chemistry & Biodiversity·Virendra S Rana, Mohan S M Rawat
Aug 19, 2007·Journal of Pharmaceutical and Biomedical Analysis·Anita AberhamMarkus Ganzera
Feb 15, 2008·Journal of Agricultural and Food Chemistry·Ann-Dorit Moltke SørensenCharlotte Jacobsen
Jan 12, 2010·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Roberto Isaac López-CruzFelipe Galván-Magaña
Jun 15, 2010·Journal of Pharmaceutical and Biomedical Analysis·Spiridon KintziosAnita Kusar
Nov 6, 2010·Journal of Pharmaceutical and Biomedical Analysis·Anita AberhamHermann Stuppner
Aug 2, 2011·Biological & Pharmaceutical Bulletin·Hisae OkuKyoko Ishiguro
Apr 24, 2012·Journal of Pharmaceutical and Biomedical Analysis·Branislav NastasijevićVesna Vasić
Nov 14, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Vladimir MihailovićSanja Matić
Aug 10, 2013·Journal of the Science of Food and Agriculture·Monika SkowyraMaría Pilar Almajano

❮ Previous
Next ❯

Citations

Jan 20, 2016·Antioxidants·Nurul Aini Mohd AzmanMaríaPilar Almajano
Apr 5, 2016·Antioxidants·Nurul Aini Mohd AzmanMaría Pilar Almajano Pablos
Aug 21, 2014·Journal of the Science of Food and Agriculture·Nurul A M AzmanMaría Pilar Almajano
Jul 8, 2016·Journal of Food Science·Francisco Segovia Gómez, María Pilar Almajano Pablos
Jul 11, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Manel OuerfelliMaría Pilar Almajano
Sep 23, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Francisco J SegoviaMaría Pilar Almajano
Jan 8, 2021·Arhiv za higijenu rada i toksikologiju·Ana Valenta ŠobotJelena Filipović Tričković
Jul 25, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Joelle MesmarElias Baydoun

❮ Previous
Next ❯

Methods Mentioned

BETA
MDA
ABTS

Software Mentioned

Minitab

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
Sindhu Mathew, T Emilia Abraham
© 2022 Meta ULC. All rights reserved